Zhang Feng, Ning Zhongxing, Wang Can
Department of Neurology, The Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Department of Intensive Care Unit, Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-sen University, Nanning, China.
Front Aging Neurosci. 2024 Nov 20;16:1466464. doi: 10.3389/fnagi.2024.1466464. eCollection 2024.
Obesity negatively impacts cognitive function. However, the correlation between the body roundness index (BRI) and cognitive performance remains inadequately explored.
This study used data from the National Health and Nutrition Examination Survey (NHANES) collected from 2011 to 2014 to examine the correlation between BRI and cognitive function in individuals aged 65 and older. Models of multiple linear regression were used to investigate the relationship between BRI and cognitive performance. Additionally, smoothed curve fittings explored potential non-linear associations. Interaction tests and subgroup analyses were also performed.
One thousand eight hundred seventy participants were taken into account, revealing an important negative relationship between BRI levels and cognitive performance. In the fully adjusted model, elevated BRI was substantially correlated with lower Digit Symbol Substitution Test (DSST) scores ( = -0.34, 95% CI = -0.64 to -0.05, = 0.023), indicating that the higher BRI values are linked to worse cognitive performance. Sex differences were observed, with males showing a stronger negative association ( for interaction = 0.040).
Elevated BRI is related to worse cognitive function in the elderly population.
肥胖对认知功能有负面影响。然而,身体圆润度指数(BRI)与认知表现之间的相关性仍未得到充分研究。
本研究使用了2011年至2014年美国国家健康与营养检查调查(NHANES)的数据,以检验65岁及以上人群中BRI与认知功能之间的相关性。使用多元线性回归模型来研究BRI与认知表现之间的关系。此外,平滑曲线拟合探索了潜在的非线性关联。还进行了交互作用检验和亚组分析。
共纳入1870名参与者,结果显示BRI水平与认知表现之间存在显著的负相关关系。在完全调整模型中,较高的BRI与较低的数字符号替换测验(DSST)分数显著相关(β = -0.34,95%置信区间 = -0.64至-0.05,P = 0.023),这表明较高的BRI值与较差的认知表现相关。观察到了性别差异,男性表现出更强的负相关(交互作用P = 0.040)。
较高的BRI与老年人群较差的认知功能有关。