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采用试纸法检测无症状学龄儿童尿液异常的患病率。

Prevalence of urinary abnormalities in asymptomatic school going children by dipstick method.

作者信息

Nawaz Hassan, Butt Noman, Anees Muhammad, Babar Kainat

机构信息

Hassan Nawaz, MBBS. Department of Nephrology, King Edward Medical University, Lahore, Pakistan.

Noman Butt, FCPS. Department of Nephrology, King Edward Medical University, Lahore, Pakistan.

出版信息

Pak J Med Sci. 2024 Dec;40(11):2480-2484. doi: 10.12669/pjms.40.11.8878.

Abstract

OBJECTIVE

To determine the prevalence of urinary abnormalities in asymptomatic school children.

METHODS

This observational study was conducted at King Edward Medical University/Mayo Hospital Lahore. Children of 5-15 year of age from Central Model School, Lower Mall, Lahore were included from March to May, 2022. Children having prior renal or systemic disease, on steroids and menstruating girls at the time of urinalysis were excluded. In first screening, children's urine was collected in clean 20mL vessel and examined using urinary dipstick. Children with aberrant results were re-screened after two weeks.

RESULT

Out of total 1600 children, majority were male 1416(88.5%) with mean age 11.92±2.47 years. Urinary abnormalities were observed in 278(17.38%) children on first screening and 86(5.38%) on second screening. Isolated proteinuria was present in 131(8.19%) children on first screening and 26(1.62%) on second screening. Isolated hematuria was present in 100(6.50%) on first screening and 33(2.06%) on second screening. Isolated pyuria was present in 24(1.50%) on first screening and 14(0.88%) on second screening. Combined proteinuria and hematuria were present in 10(0.62%) on first screening and two (0.12%) on second screening. Combined proteinuria and pyuria were present in three (0.19%) on first screening and three (0.19%) on second screening. Combined hematuria and pyuria were present in nine (0.56%) on first screening and five (0.31%) on second screening. Combined proteinuria, hematuria and pyuria was present in one (0.06%) on first screening and three (0.19%) on second screening.

CONCLUSION

Urine screening is necessary for early detection and management of kidney diseases. Marked number of children was found having urinary abnormalities. Asymptomatic proteinuria was the most common finding reflecting underlying kidney pathology going undiagnosed.

摘要

目的

确定无症状学龄儿童尿液异常的患病率。

方法

本观察性研究在拉合尔爱德华国王医科大学/梅奥医院进行。2022年3月至5月纳入了来自拉合尔下商城中央模范学校的5至15岁儿童。排除既往有肾脏或全身性疾病、正在使用类固醇的儿童以及尿检时处于经期的女孩。在首次筛查中,将儿童尿液收集到干净的20毫升容器中,并用尿试纸进行检测。结果异常的儿童在两周后重新进行筛查。

结果

在总共1600名儿童中,大多数为男性,共1416名(88.5%),平均年龄为11.92±2.47岁。首次筛查时,278名(17.38%)儿童存在尿液异常,第二次筛查时为86名(5.38%)。首次筛查时,131名(8.19%)儿童存在单纯蛋白尿,第二次筛查时为26名(1.62%)。首次筛查时,100名(6.50%)儿童存在单纯血尿,第二次筛查时为33名(2.06%)。首次筛查时,24名(1.50%)儿童存在单纯脓尿,第二次筛查时为14名(0.88%)。首次筛查时,10名(0.62%)儿童存在蛋白尿合并血尿,第二次筛查时为2名(0.12%)。首次筛查时,3名(0.19%)儿童存在蛋白尿合并脓尿,第二次筛查时为3名(0.19%)。首次筛查时,9名(0.56%)儿童存在血尿合并脓尿,第二次筛查时为5名(0.31%)。首次筛查时,1名(0.06%)儿童存在蛋白尿、血尿和脓尿合并情况,第二次筛查时为3名(0.19%)。

结论

尿液筛查对于肾脏疾病的早期发现和管理是必要的。发现有相当数量的儿童存在尿液异常。无症状蛋白尿是最常见的发现,反映了潜在的肾脏病变未被诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e671/11613395/aeb21244c5bf/PJMS-40-2480-g002.jpg

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