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全膝关节置换术患者术后运动恐惧的影响因素分析及列线图预测模型的构建

Analysis of influencing factors and construction of nomogram prediction model of postoperative kinesiophobia in patients undergoing total knee arthroplasty.

作者信息

Xie Jian, Cai Haoliang, Chen Wenting, Wu Xiaohui, Chen Xi, Guo Jun

机构信息

Jian Xie, Dept. of Anesthesiology, Shuguang Hospital Affiliated to Shanghai, University of Traditional Chinese Medicine, Shanghai 201203, P.R. China.

Haoliang Cai, Dept. of Anesthesiology, Shuguang Hospital Affiliated to Shanghai, University of Traditional Chinese Medicine, Shanghai 201203, P.R. China.

出版信息

Pak J Med Sci. 2024 Dec;40(11):2550-2557. doi: 10.12669/pjms.40.11.10306.

Abstract

OBJECTIVE

To explore the influencing factors of kinesiophobia and to establish a nomogram prediction model.

METHODS

A retrospective observational study was conducted in 354 patients who underwent TKA in Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from December 2019 to December 2022. Sociodemographic characteristics, anesthesia methods, Tampa Scale for Kinesiophobia (TSK), numeric rating scale (NRS), hospital for special surgery (HSS), activities of daily living (ADL), and self-rating anxiety scale (SAS) were reviewed and analyzed. Logistic regression analysis was used to identify the influencing factors of kinesiophobia, and a nomogram model was established based on the identified influencing factors and verified by consistency index (C-index), calibration curve, and receiver operating characteristic (ROC) curve.

RESULTS

Incidence of kinesiophobia in patients who received TEAS combined with western medicine (dexmedetomidine and remifentanil) was significantly lower than that in patients who received western medicine alone. The logistic regression analysis showed that family monthly income level, HSS, ADL, and combined TEAS and western medicine approach were independent protective factors for kinesiophobia (all <0.05). The degree of pain and anxiety were independent risk factors for kinesiophobia (both <0.05). A nomogram model was constructed with C-index of 0.721 (0.658, 0.784), and the area under curve (AUC) was 0.748 (95 %CI: 0.685-0.807). The calibration curve also showed good consistency between actual observations and nomogram model predictions.

CONCLUSIONS

Family monthly income level, anesthesia methods, NRS, HSS, ADL, and SAS scores are influencing factors of kinesiophobia, and the nomogram model can be useful for predicting postoperative kinesiophobia.

摘要

目的

探讨运动恐惧的影响因素并建立列线图预测模型。

方法

对2019年12月至2022年12月在上海中医药大学附属曙光医院接受全膝关节置换术(TKA)的354例患者进行回顾性观察研究。回顾并分析社会人口学特征、麻醉方法、坦帕运动恐惧量表(TSK)、数字评定量表(NRS)、特种外科医院(HSS)评分、日常生活活动能力(ADL)及自评焦虑量表(SAS)。采用Logistic回归分析确定运动恐惧的影响因素,并基于所确定的影响因素建立列线图模型,通过一致性指数(C指数)、校准曲线和受试者工作特征(ROC)曲线进行验证。

结果

接受经皮穴位电刺激(TEAS)联合西药(右美托咪定和瑞芬太尼)治疗的患者运动恐惧发生率显著低于单纯接受西药治疗的患者。Logistic回归分析显示,家庭月收入水平、HSS评分、ADL及TEAS联合西药治疗方法是运动恐惧的独立保护因素(均P<0.05)。疼痛程度和焦虑是运动恐惧的独立危险因素(均P<0.05)。构建的列线图模型C指数为0.721(0.658,0.784),曲线下面积(AUC)为0.748(95%CI:0.685 - 0.807)。校准曲线也显示实际观察结果与列线图模型预测之间具有良好的一致性。

结论

家庭月收入水平、麻醉方法、NRS评分、HSS评分、ADL及SAS评分是运动恐惧的影响因素,列线图模型可用于预测术后运动恐惧。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8934/11613390/d3c98ed072a3/PJMS-40-2550-g001.jpg

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