Bai Xue, Wang Hui, Li Jiangzhe, Xu Jinjin, Cai Pan
Xue Bai Department of Physical Examination, Baoding No.1 Central Hospital, Baoding 071000, Hebei, China.
Hui Wang Department of Urological, Baoding No.1 Central Hospital, Baoding 071000, Hebei, China.
Pak J Med Sci. 2024 Dec;40(11):2533-2537. doi: 10.12669/pjms.40.11.9563.
To explore the correlation between the risk of ischemic stroke and related risk factors in a health examination population.
This was a retrospective study. A total of 300 subjects undergoing health examination in the physical examination center of Baoding NO.1 Central Hospital were selected from January 2023 to December 2023, and divided into the normal group (Group-N) and the risk group according to the criteria of cerebral hemodynamic integral value(CVHI). The risk group was further subdivided into three groups, including the high-risk group(Group-H), the medium-risk population(Group-M), and the low-risk group(Group-L), with 75 subjects in each group. The general data, including BMI, smoking, and the incidence of hypertension, diabetes, and hyperlipidemia, were analyzed and compared between the two groups.
Multivariable logistic regression analysis was conducted using stroke risk factors as the dependent variables after assignment, and it was found that BMI, smoking, hypertension, diabetes, hyperlipidemia, and hyperuricemia were independent risk factors for ischemic stroke (P<0.05); the incidence of obesity and overweight, smoking, hypertension, hyperlipidemia, and hyperuricemia were significantly increased in Group-H compared with those in groups M, L, and N, with statistically significant differences(P<0.05). The chi square test showed statistically significant differences in the stroke risk factors among different age groups (P<0.05).
The incidence of ischemic stroke risk factors varies among different age groups in the health examination population, and is related to poor lifestyle and underlying diseases.
探讨健康体检人群中缺血性脑卒中风险与相关危险因素之间的相关性。
本研究为回顾性研究。选取2023年1月至2023年12月在保定市第一中心医院体检中心进行健康体检的300名受试者,根据脑血流动力学积分值(CVHI)标准分为正常组(N组)和风险组。风险组进一步细分为三组,包括高危组(H组)、中危人群(M组)和低危组(L组),每组75名受试者。分析并比较两组之间的一般资料,包括体重指数、吸烟情况以及高血压、糖尿病和高脂血症的发病率。
以脑卒中危险因素为赋值后的因变量进行多变量logistic回归分析,发现体重指数、吸烟、高血压、糖尿病、高脂血症和高尿酸血症是缺血性脑卒中的独立危险因素(P<0.05);与M组、L组和N组相比,H组肥胖和超重、吸烟、高血压、高脂血症和高尿酸血症的发病率显著升高,差异有统计学意义(P<0.05)。卡方检验显示不同年龄组的脑卒中危险因素差异有统计学意义(P<0.05)。
健康体检人群中缺血性脑卒中危险因素的发生率在不同年龄组中存在差异,且与不良生活方式和基础疾病有关。