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药师在慢性阻塞性肺疾病出院时开具吸入器处方对再入院率的影响。

Impact of Pharmacist Inhaler Prescribing at Discharge for Chronic Obstructive Pulmonary Disease on Readmission Rates.

作者信息

Diaz Ana-Maria, Smith Lindsey M, Peterson Amber N, Kent Macie L, Vellian Namitha J

机构信息

Lakeland Regional Health, Lakeland, Florida, United States.

出版信息

Chronic Obstr Pulm Dis. 2025 Jan 29;12(1):43-51. doi: 10.15326/jcopdf.2024.0553.

Abstract

BACKGROUND

Acute exacerbation of chronic obstructive pulmonary disease (COPD) is one of the 6 conditions in the Hospital Readmissions Reduction Program for which institutions are penalized for high 30-day readmission rates. This institution's transitions of care (TOC) pharmacists have prescribing authority to optimize guideline-directed medical therapy (GDMT), defined as discharging on rescue plus triple therapy inhalers under an approved protocol. While several studies evaluate the impact of pharmacist-led interventions on COPD readmission rates, there is a lack of literature with respect to pharmacists prescribing inhalers under an approved protocol. This study aims to evaluate all-cause 30-day COPD readmission rates.

METHODS

This was an institutional review board-approved, single-center, retrospective evaluation conducted between May 2021 and August 2023. Patients were included if they met criteria under the Centers for Medicare and Medicaid Services Hospital Readmissions Reduction Program COPD model. Patients in the pre-implementation group received usual care, with postdischarge nurse follow-up while patients in the postimplementation group received TOC pharmacy services. The primary outcome was all-cause 30-day readmission rates. Secondary outcomes included readmission reason and proportion of patients discharged on GDMT.

RESULTS

A total of 279 patients were included, with 187 patients in the pre-implementation group and 92 patients in the postimplementation group. All-cause 30-day readmission rates in the pre- and postimplementation groups were 26% and 14%, respectively (=0.02). The proportion of patients discharged on GDMT was 26% in the pre-implementation group and 100% in the postimplementation group (<0.001).

CONCLUSION

Utilizing a TOC pharmacy service may be associated with a reduction in all-cause 30-day readmission rates for patients with COPD.

摘要

背景

慢性阻塞性肺疾病(COPD)急性加重是“降低医院再入院率计划”中的6种病症之一,医疗机构若30天再入院率过高将受到处罚。该机构的护理转接(TOC)药师拥有处方权,可优化指南指导的药物治疗(GDMT),即按照批准的方案在出院时开具急救药物加三联吸入器。虽然有多项研究评估了药师主导的干预措施对COPD再入院率的影响,但缺乏关于药师按照批准方案开具吸入器的文献。本研究旨在评估全因30天COPD再入院率。

方法

这是一项经机构审查委员会批准的单中心回顾性评估,于2021年5月至2023年8月进行。符合医疗保险和医疗补助服务中心医院再入院率降低计划COPD模型标准的患者被纳入研究。实施前组的患者接受常规护理,出院后由护士随访,而实施后组的患者接受TOC药学服务。主要结局是全因30天再入院率。次要结局包括再入院原因和出院时接受GDMT治疗的患者比例。

结果

共纳入279例患者,其中实施前组187例,实施后组92例。实施前组和实施后组的全因30天再入院率分别为26%和14%(=0.02)。实施前组出院时接受GDMT治疗的患者比例为26%,实施后组为100%(<0.001)。

结论

利用TOC药学服务可能会降低COPD患者的全因30天再入院率。

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本文引用的文献

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What the pulmonary specialist should know about the new inhalation therapies.肺部专家应该了解的新型吸入疗法。
Eur Respir J. 2011 Jun;37(6):1308-31. doi: 10.1183/09031936.00166410. Epub 2011 Feb 10.

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