Kim Jennifer, Lin Amy, Absher Randy, Makhlouf Tanya, Wells Casey
Cone Health, Greensboro, North Carolina, United States.
Area Health Education Center, Greensboro, North Carolina, United States.
Chronic Obstr Pulm Dis. 2021 Jan;8(1):152-61. doi: 10.15326/jcopdf.2019.0175.
Mortality risk from chronic obstructive pulmonary disease (COPD) increases significantly in the first year after a 30-day hospital readmission.
To evaluate a comprehensive and collaborative pharmacist transitions of care service for patients hospitalized with COPD compared to usual care.
In this within-site, retrospective study, discharge counseling, medication reconciliation, medication access assistance, therapy changes, and post-discharge long-term follow-up were provided to underserved adult patients with a primary care provider at the study clinic and admitted to the affiliated hospital with a primary diagnosis of COPD exacerbation. Primary outcome was a 180-day composite of COPD-related hospitalizations and emergency department (ED) visits. Secondary outcomes were 30-, 60-, 90-, and 180-day events, costs, pharmacist interventions, time to follow-up, and pneumonia.
Sixty-five patients were identified with a total of 101 index admissions. The mean age was 62.5 years, approximately 55.3% were female, and 67.7% were black or African American. The primary composite was significantly lower in the pharmacist intervention group compared to usual care (mean difference 0.82, =0.0364, 95% confidence interval [CI] 0.05-1.60), driven by lower 30-day hospitalizations in the intervention group (mean difference 0.15, =0.0099, 95% CI 0.04-0.27). Cost associated with COPD-related hospitalizations was significantly lower in the pharmacist intervention group compared to usual care ($173,808, = 0.0330) as well as before intervention ($79,662, =0.0233). There was no significant difference in time to follow-up or pneumonia.
A comprehensive, collaborative pharmacist transitions of care service significantly reduced 30-day COPD-related hospital readmissions, ED re-visits, and associated costs in an underserved population.
慢性阻塞性肺疾病(COPD)患者在30天内再次入院后的第一年,死亡风险显著增加。
评估为因COPD住院的患者提供的全面协作的药师护理过渡服务与常规护理相比的效果。
在这项现场回顾性研究中,为在研究诊所设有初级保健提供者且因COPD急性加重而入住附属医院的未得到充分服务的成年患者提供出院咨询、用药核对、用药获取协助、治疗调整以及出院后长期随访。主要结局是COPD相关住院和急诊科(ED)就诊的180天综合指标。次要结局是30天、60天、90天和180天的事件、费用、药师干预、随访时间以及肺炎。
共确定65例患者,总计101次索引入院。平均年龄为62.5岁,约55.3%为女性,67.7%为黑人或非裔美国人。与常规护理相比,药师干预组的主要综合指标显著更低(平均差值0.82,P = 0.0364,95%置信区间[CI] 0.05 - 1.60),这是由干预组较低的30天住院率驱动的(平均差值0.15,P = 0.0099,95% CI 0.04 - 0.27)。与常规护理相比,药师干预组与COPD相关住院的费用显著更低(173,808美元,P = 0.0330),与干预前相比也更低(79,662美元,P = 0.0233)。随访时间或肺炎方面无显著差异。
全面协作的药师护理过渡服务显著降低了未得到充分服务人群中30天COPD相关再入院率、急诊科再就诊率及相关费用。