Takatsu Jun, Chiba Takahito, Murakami Naoya, Iijima Kotaro, Inoue Tatsuya, Okonogi Noriyuki, Muramoto Yoichi, Kawamoto Terufumi, Karino Tatsuki, Okamoto Hiroyuki, Nakamura Satoshi, Nakayama Hiroki, Terao Yasuhisa, Shikama Naoto
Department of Radiation Oncology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Radiation Safety and Quality Assurance Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Radiol Phys Technol. 2025 Mar;18(1):329-336. doi: 10.1007/s12194-024-00867-x. Epub 2024 Dec 5.
This study developed a system to reduce the treatment planning time for cervical cancer brachytherapy. An in-house Excel spreadsheet was developed to streamline dosimetric evaluation by combining external beam radiotherapy and brachytherapy doses, while also displaying daily dose constraints, a novel feature of the system. This system was validated in 46 consecutive patients who underwent intracavitary and interstitial brachytherapy using several applicators and required more complex dose calculation procedures than intracavitary brachytherapy alone. The proposed system included contouring and catheter reconstruction using multiple treatment planning systems simultaneously and was integrated with Excel spreadsheets for rapid dosimetric evaluation. The median time required for treatment planning was 36 min (range: 12-72 min), which was a much shorter time than those reported previously. This optimized system demonstrated the potential to increase the efficiency of brachytherapy planning to meet prescribed dose constraints without compromising treatment quality.
本研究开发了一种系统，以减少宫颈癌近距离放疗的治疗计划时间。开发了一个内部Excel电子表格，通过结合外照射放疗和近距离放疗剂量来简化剂量学评估，同时还显示每日剂量限制，这是该系统的一个新特点。该系统在46例连续接受腔内和组织间近距离放疗的患者中得到验证，这些患者使用了多种施源器，并且需要比单纯腔内近距离放疗更复杂的剂量计算程序。所提出的系统包括同时使用多个治疗计划系统进行轮廓勾画和导管重建，并与Excel电子表格集成以进行快速剂量学评估。治疗计划所需的中位时间为36分钟（范围：12 - 72分钟），这比之前报道的时间要短得多。这种优化后的系统显示出在不影响治疗质量的前提下，提高近距离放疗计划效率以满足规定剂量限制的潜力。
