Wycoff Andrea M, Darmour Charles A, McCarthy Denis M, Trull Timothy J
Department of Psychiatry, University of Missouri.
Department of Psychological Sciences, University of Missouri.
Exp Clin Psychopharmacol. 2025 Apr;33(2):170-177. doi: 10.1037/pha0000758. Epub 2024 Dec 5.
Alcohol-impaired driving is highly prevalent and a leading cause of death. Cannabis is commonly used among people who drink alcohol, and using alcohol and cannabis simultaneously is associated with a greater frequency of alcohol-impaired driving. Laboratory studies demonstrate the harmful effects of simultaneous use on driving ability compared to alcohol use alone, yet driving under the influence of cannabis is perceived as a low risk. We tested the influences of alcohol, cannabis, and their simultaneous use on perceived driving impairment and willingness to drive in daily life. Participants were 88 adults aged 18-44 ( = 25.22 years, 60.2% female, 85.2% White) who reported using alcohol and cannabis simultaneously at least twice per week. They completed 14 days of ecological momentary assessment and reported their alcohol and cannabis use, perceived driving impairment, and willingness to drive "right now" and "1 hr from now" on an average of 5.14 surveys per day. Adjusting for the total amount of alcohol consumed, results from multilevel models include greater perceived driving impairment when using alcohol ( = 0.39, = 0.05, < .001) and cannabis ( = 0.37, = 0.03, < .001) separately, but greater odds of being willing to drive right now (OR = 2.29, 95% CI [1.38, 3.81], = .001) and in 1 hr (OR = 3.69, 95% CI [2.15, 6.34], < .001) when using alcohol and cannabis simultaneously compared to using alcohol by itself. Simultaneous use of cannabis may attenuate the impact of alcohol on the decision to drive and may contribute harmfully to in-the-moment decisions to drive under the influence of alcohol. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
酒后驾车非常普遍,是主要的死亡原因。大麻在饮酒者中普遍使用,同时使用酒精和大麻与酒后驾车的频率更高有关。实验室研究表明,与单独使用酒精相比,同时使用会对驾驶能力产生有害影响,但在大麻影响下驾车被视为低风险行为。我们测试了酒精、大麻及其同时使用对日常生活中感知到的驾驶障碍和驾驶意愿的影响。参与者为88名年龄在18 - 44岁之间的成年人(平均年龄 = 25.22岁,60.2%为女性,85.2%为白人),他们报告每周至少同时使用酒精和大麻两次。他们完成了14天的生态瞬时评估,并报告了他们的酒精和大麻使用情况、感知到的驾驶障碍以及在“现在”和“1小时后”的驾驶意愿,每天平均进行5.14次调查。在调整酒精消费总量后,多层次模型的结果显示,单独使用酒精(β = 0.39,SE = 0.05,p <.001)和大麻(β = 0.37,SE = 0.03,p <.001)时,感知到的驾驶障碍更大,但与单独使用酒精相比,同时使用酒精和大麻时,当下(OR = 2.29,95% CI [1.38, 3.81],p =.001)和1小时后(OR = 3.69,95% CI [2.15, 6.34],p <.001)愿意驾车的几率更高。同时使用大麻可能会减弱酒精对驾驶决策的影响,并可能对在酒精影响下当下的驾驶决策产生有害影响。(PsycInfo数据库记录(c)2025美国心理学会,保留所有权利)