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非典型科根综合征:一种自身免疫性疾病?

Atypical Cogan's syndrome: an autoimmune disease?

作者信息

Peeters G J, Cremers C W, Pinckers A J, Hoefnagels W H

出版信息

Ann Otol Rhinol Laryngol. 1986 Mar-Apr;95(2 Pt 1):173-5. doi: 10.1177/000348948609500213.

DOI:10.1177/000348948609500213
PMID:3963689
Abstract

A 22-year-old woman is described with gastrointestinal complaints, sclerokeratitis, and a bilateral progressive hearing loss. The clinical picture, the outcome of lymphocyte stimulation tests against S antigen (retina soluble antigen), outer rod segment, and scleroprotein, and the successful administration of corticosteroids after a partial spontaneous hearing improvement, are suggestive of an autoimmune disease.

摘要

一名22岁女性出现胃肠道不适、巩膜角膜炎和双侧进行性听力丧失。临床表现、针对S抗原(视网膜可溶性抗原)、外节杆段和硬蛋白的淋巴细胞刺激试验结果,以及在听力部分自发改善后成功使用皮质类固醇治疗,提示为自身免疫性疾病。

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Atypical Cogan's syndrome: an autoimmune disease?非典型科根综合征:一种自身免疫性疾病?
Ann Otol Rhinol Laryngol. 1986 Mar-Apr;95(2 Pt 1):173-5. doi: 10.1177/000348948609500213.
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Acute autoimmune sensorineural hearing loss associated with Crohn's disease.与克罗恩病相关的急性自身免疫性感音神经性听力损失
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Atypical Cogan's syndrome: a case report.非典型 Cogan 综合征:一例报告。
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Course of auditory impairment in Cogan's syndrome.科根综合征的听力损害病程。
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[Cogan's syndrome. Recovery from sudden hearing loss after prompt treatment with corticosteroids].[科根综合征。经皮质类固醇迅速治疗后突发性听力损失的恢复情况]
Med Clin (Barc). 1985 May 4;84(17):694-6.
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Cogan's syndrome manifesting as sudden bilateral deafness: diagnosis and management.表现为突发性双侧耳聋的科根综合征:诊断与管理
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Atypical Cogan's syndrome successfully treated with corticosteroids and pulse cyclophosphamide therapy.
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引用本文的文献

1
Autoimmune vertigo: an update on vestibular disorders associated with autoimmune mechanisms.自身免疫性眩晕:与自身免疫机制相关的前庭障碍的最新进展。
Immunol Res. 2018 Dec;66(6):675-685. doi: 10.1007/s12026-018-9023-6.
2
Rituximab ameliorated severe hearing loss in Cogan's syndrome: a case report.利妥昔单抗改善 Cogan 综合征重度听力损失:病例报告。
Orphanet J Rare Dis. 2010 Jun 16;5:18. doi: 10.1186/1750-1172-5-18.
3
[Cogan's syndrome: a diagnostic challenge].[科根综合征:一项诊断挑战]
HNO. 2006 Aug;54(8):619-23. doi: 10.1007/s00106-005-1316-0.
4
Cogan's syndrome: an oculo-audiovestibular disease.科根综合征:一种眼-耳-前庭疾病。
Postgrad Med J. 1999 May;75(883):262-4. doi: 10.1136/pgmj.75.883.262.