非典型科根综合征：一种自身免疫性疾病？

Atypical Cogan's syndrome: an autoimmune disease?

作者信息

Peeters G J, Cremers C W, Pinckers A J, Hoefnagels W H

出版信息

Ann Otol Rhinol Laryngol. 1986 Mar-Apr;95(2 Pt 1):173-5. doi: 10.1177/000348948609500213.

Abstract

A 22-year-old woman is described with gastrointestinal complaints, sclerokeratitis, and a bilateral progressive hearing loss. The clinical picture, the outcome of lymphocyte stimulation tests against S antigen (retina soluble antigen), outer rod segment, and scleroprotein, and the successful administration of corticosteroids after a partial spontaneous hearing improvement, are suggestive of an autoimmune disease.

摘要

一名22岁女性出现胃肠道不适、巩膜角膜炎和双侧进行性听力丧失。临床表现、针对S抗原（视网膜可溶性抗原）、外节杆段和硬蛋白的淋巴细胞刺激试验结果，以及在听力部分自发改善后成功使用皮质类固醇治疗，提示为自身免疫性疾病。