Schneider J S, Diamond S G, Markham C H
Ann Neurol. 1986 Mar;19(3):275-82. doi: 10.1002/ana.410190309.
Orofacial sensorimotor function was assessed in patients with Parkinson's disease and in age-matched controls. Tests were designed to assess sensory function, motor abilities, and the integration of sensory information for the performance of specific movements. Patients with Parkinson's disease and normal subjects both made more errors with increasing age; however, overall, patients with Parkinson's disease made significantly more errors in our tests than did normal subjects. Interestingly, patients with Parkinson's disease showed greater deficits in tests of sensory function and sensorimotor integration than in tests of motor function. These results suggest that one aspect of Parkinson's disease consists of complex deficits in the utilization of specific sensory inputs to organize and guide movements. The results are further discussed in relation to a proposed sensory gating or filtering schema of basal ganglia motor functioning.
对帕金森病患者和年龄匹配的对照组进行了口面部感觉运动功能评估。测试旨在评估感觉功能、运动能力以及特定运动表现中感觉信息的整合情况。帕金森病患者和正常受试者都随着年龄增长出现更多错误；然而，总体而言，在我们的测试中，帕金森病患者比正常受试者出现的错误明显更多。有趣的是，帕金森病患者在感觉功能和感觉运动整合测试中的缺陷比在运动功能测试中更大。这些结果表明，帕金森病的一个方面包括在利用特定感觉输入来组织和指导运动方面存在复杂缺陷。结合提出的基底神经节运动功能的感觉门控或过滤模式，对结果进行了进一步讨论。
