Yan Zhen, Yang Songyi, Lin Chen, Yan Jin, Liu Meng, Tang Si, Jia Weitao, Liu Jianquan, Liu Huanhuan
Key Laboratory for Bio-resources and Eco-environment & State Key Lab of Hydraulics & Mountain River Engineering, Sichuan Zoige Alpine Wetland Ecosystem National Observation and Research Station, Key Laboratory for Bio-resource and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan 610065, China; National Demonstration Center for Experimental Biology Education (Sichuan University), Chengdu, Sichuan 610065, China.
Key Laboratory for Bio-resources and Eco-environment & State Key Lab of Hydraulics & Mountain River Engineering, Sichuan Zoige Alpine Wetland Ecosystem National Observation and Research Station, Key Laboratory for Bio-resource and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan 610065, China.
J Genet Genomics. 2025 May;52(5):615-627. doi: 10.1016/j.jgg.2024.11.014. Epub 2024 Dec 9.
Oxygen is essential for the biochemical processes that sustain life in eukaryotic organisms. Although plants produce oxygen through photosynthesis, they often struggle to survive in low-oxygen environments, such as during flooding or submergence. To endure these conditions, they must reprogram their developmental and metabolic networks, and the adaptation process involves the continuous detection of both exogenous hypoxic signals and endogenous oxygen gradients. Recent research has significantly advanced our understanding of how plants respond to both endogenous and exogenous hypoxia signals. In this review, we explore advancements in both areas, comparing them to responses in animals, with a primary focus on how plants perceive and respond to exogenous hypoxic conditions, particularly those caused by flooding or submergence, as well as the hypoxia signaling pathways in different crops. Additionally, we discuss the interplay between endogenous and exogenous hypoxia signals in plants. Finally, we discuss future research directions aimed at improving crop resilience to flooding by integrating the perception and responses to both endogenous and exogenous signals. Through these efforts, we aspire to contribute to the development of crop varieties that are not only highly resistant but also experience minimal growth and yield penalties, thereby making substantial contributions to agricultural science.
氧气对于维持真核生物生命的生化过程至关重要。尽管植物通过光合作用产生氧气，但它们在低氧环境中（如洪水或淹没期间）往往难以存活。为了在这些条件下生存，它们必须重新编程其发育和代谢网络，而适应过程涉及对外源低氧信号和内源氧梯度的持续检测。最近的研究极大地推进了我们对植物如何对内源和外源低氧信号作出反应的理解。在本综述中，我们探讨这两个领域的进展，将它们与动物的反应进行比较，主要关注植物如何感知和应对外源低氧条件，特别是由洪水或淹没引起的低氧条件，以及不同作物中的低氧信号通路。此外，我们还讨论了植物内源和外源低氧信号之间的相互作用。最后，我们讨论旨在通过整合对内源和外源信号的感知与反应来提高作物抗涝能力的未来研究方向。通过这些努力，我们希望为不仅具有高度抗性而且生长和产量损失最小的作物品种的开发做出贡献，从而为农业科学做出重大贡献。
