Jung Clarissa, Gentil Michaela, Müller Elisabeth
Laboklin GmbH & Co. KG, Bad Kissingen, Germany.
Tierarztl Prax Ausg G Grosstiere Nutztiere. 2024 Dec;52(6):327-335. doi: 10.1055/a-2450-9531. Epub 2024 Dec 5.
The objective of the study was to investigate the age dependent occurrence of different infectious agents in foals with diarrhea.
Fecal samples, which were submitted to a commercial laboratory for a PCR-profile "Foal Diarrhea Pathogens" from 01.01.2021 up to 31.12.2022 (n=144), were examined for Equine Coronavirus (ECoV), , (), toxin-encoding genes , , , and , toxin-encoding genes and , as well as Rotavirus A via PCR.
Pathogens could be detected in a high proportion (42.9%) of the samples. Rotavirus A was the most prevalent pathogen in the current study, followed by clostridial species. Especially in foals younger than one month, -producing was detected frequently. In this age group, -producing was as prevalent as Rotavirus A. In comparison, , and ECoV were detected rarely. toxin-encoding genes and were not present in the examined samples. In general, the previously known age dependency of the investigated pathogens could be confirmed. Nevertheless, Rotavirus A and -positive could also be detected outside of the most susceptible age group. Coinfections with the examined pathogens had a low prevalence in the current study.
In general, the examined pathogens showed an age dependent occurrence, but infections in foals outside of the common age group could not be ruled out with certainty due to small sample numbers in some of the age groups. Although Rotavirus A was the most prevalent pathogen in this study, -producing is an important differential diagnosis, especially in newborn foals. The diagnostic approach in diarrheic foals should contain a broad spectrum of pathogens. This is not only important to detect coinfections, but also to detect shedders, in order to protect other horses in the stable.
本研究的目的是调查腹泻马驹中不同感染因子的年龄依赖性发生情况。
2021年1月1日至2022年12月31日提交给商业实验室进行“马驹腹泻病原体”PCR检测的粪便样本（n = 144），通过PCR检测马冠状病毒（ECoV）、、（）、毒素编码基因、、、和、毒素编码基因以及A组轮状病毒。
在高比例（42.9%）的样本中可检测到病原体。A组轮状病毒是本研究中最常见的病原体，其次是梭菌属。特别是在1月龄以下的马驹中，经常检测到产的。在这个年龄组中，产的与A组轮状病毒一样常见。相比之下，、和ECoV很少被检测到。在所检测的样本中不存在毒素编码基因和。总体而言，可以证实所研究病原体先前已知的年龄依赖性。然而，在最易感年龄组之外也可检测到A组轮状病毒和阳性。在本研究中，所检测病原体的合并感染患病率较低。
总体而言，所检测的病原体呈现年龄依赖性发生，但由于某些年龄组样本数量较少，不能确定排除常见年龄组以外马驹的感染。尽管A组轮状病毒是本研究中最常见的病原体，但产的是重要的鉴别诊断因素，尤其是在新生马驹中。腹泻马驹的诊断方法应涵盖广泛的病原体。这不仅对于检测合并感染很重要，而且对于检测排毒者以保护马厩中的其他马匹也很重要。
