Frasier Kelly M, Herrick Grace, Patel Hiral, Kakarla Sriya, Danial Lana, Vaishnavi Konagalla Sri, Patel Niralee
Dermatology, Northwell Health, New Hyde Park, USA.
Dermatology, Alabama College of Osteopathic Medicine, Dothan, USA.
Cureus. 2024 Nov 4;16(11):e72986. doi: 10.7759/cureus.72986. eCollection 2024 Nov.
Retention in dermatological clinical trials is critical for ensuring the validity and reliability of study outcomes, yet participant dropout remains a pervasive challenge. In this analysis, the primary aim is to explore the psychological mechanisms underpinning the efficacy of a buddy system in enhancing retention rates in such trials. The buddy system, where participants are paired with peers who have previously participated in similar clinical trials offers mutual support and leverages the principles of social bonding, accountability, and shared experience to foster commitment and reduce attrition. The novelty of this approach lies in its focus on the psychological and emotional dimensions of trial participation, rather than solely on logistical or incentive-based strategies. Implementing a buddy system draws on theories of social support and motivation, suggesting that the presence of a buddy can alleviate anxiety, increase perceived value, and enhance the overall clinical trial experience. Future research should investigate the long-term effects of buddy systems across diverse demographic groups and dermatological conditions, as well as potential adaptations for virtual trial settings. In conclusion, integrating a buddy system into dermatological clinical trials represents an innovative strategy that could significantly improve retention, thereby strengthening the robustness of clinical data and advancing dermatological research.
在皮肤病学临床试验中,保持受试者参与对于确保研究结果的有效性和可靠性至关重要,但受试者退出仍然是一个普遍存在的挑战。在本分析中,主要目的是探讨伙伴系统在提高此类试验中保留率方面发挥作用的心理机制。伙伴系统是指让受试者与之前参与过类似临床试验的同伴配对,该系统提供相互支持,并利用社会联系、责任感和共同经历的原则来促进受试者的参与并减少退出。这种方法的新颖之处在于它关注试验参与的心理和情感层面,而不仅仅是后勤或基于激励的策略。实施伙伴系统借鉴了社会支持和动机理论,表明有伙伴在场可以减轻焦虑、增加感知价值并提升整体临床试验体验。未来的研究应调查伙伴系统在不同人口群体和皮肤病状况中的长期影响,以及针对虚拟试验环境的潜在调整。总之,将伙伴系统纳入皮肤病学临床试验是一种创新策略,可显著提高保留率,从而增强临床数据的稳健性并推动皮肤病学研究。