Anami Hidenori, Shiwa Tomoko, Nonaka Taku, Nakano Hiroshi, Hashimoto Ryosuke, Yamada Masatoshi, Kobayashi Tomonori
Department of Neurosurgery, Ebina General Hospital, Ebina, Japan.
Department of Pathology, Ebina General Hospital, Ebina, Japan.
Surg Neurol Int. 2024 Nov 15;15:423. doi: 10.25259/SNI_403_2024. eCollection 2024.
Adenoid cystic carcinoma (ACC) of the parotid gland often manifests as distant metastasis long after the initial surgery, resulting in a poor long-term prognosis. The most common sites of metastasis are the lungs, liver, and bones. Single intracranial metastasis is very rare.
A 43-year-old woman with a history of surgical removal of ACC 24 years prior presented with Gerstmann syndrome and right hemianopsia. Head magnetic resonance imaging revealed a solitary extra-axial tumor in the left occipital region. The tumor was surgically removed and pathologically diagnosed as a metastasis of cribriform-type ACC. Since she had no other systemic metastasis, she did not receive adjuvant treatment and has remained recurrence-free for 35 months postoperatively.
Very late intracranial solitary metastasis of ACC is extremely rare. Due to the risk of delayed recurrence in pathologically confirmed cribriform type ACC, long-term follow-up is recommended.
腮腺腺样囊性癌（ACC）常在初次手术后很长时间才出现远处转移，导致长期预后较差。最常见的转移部位是肺、肝和骨骼。单发颅内转移非常罕见。
一名43岁女性，24年前有ACC手术切除史，现出现格斯特曼综合征和右侧偏盲。头部磁共振成像显示左枕叶有一个孤立的轴外肿瘤。该肿瘤经手术切除，病理诊断为筛状型ACC转移瘤。由于她没有其他全身转移，未接受辅助治疗，术后35个月一直无复发。
ACC非常晚期的颅内单发转移极为罕见。鉴于病理确诊为筛状型ACC有延迟复发的风险，建议进行长期随访。
