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枕部头皮中部巨大隆突性皮肤纤维肉瘤:一例罕见病例报告。

Giant scalp dermatofibrosarcoma protuberans at mid-occipital scalp: A rare case report.

作者信息

Hakim Muhammad Luqman Nul, Tjahjono Firman Priguna, Faried Ahmad

机构信息

Department of Neurosurgery, Padjadjaran University/Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.

出版信息

Surg Neurol Int. 2024 Nov 15;15:414. doi: 10.25259/SNI_604_2024. eCollection 2024.

DOI:10.25259/SNI_604_2024
PMID:39640351
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11618792/
Abstract

BACKGROUND

Dermatofibrosarcoma protuberans (DFSP) is a rare type of skin cancer that arises in the deeper layers of the skin, most commonly on the trunk and limbs. The presentation of DFSP on the scalp is worth documentation due to its extremely rare occurrence in the literature.

CASE DESCRIPTION

We describe a case of a 41-year-old female presented with a lump on the back of the head with gradual enlargement. It was solitary with a size 19 × 12 × 10 cm with purulent discharge and intermittent pain. A computed tomography-scan showed an isodense mass at mid occipital without intracranial involvement. Tumor extirpation and the free flap were performed collaborated with plastic surgery. The patient was discharged unremarkably on the 7 postoperative day without any neurological deficits.

CONCLUSION

Our case is distinct because, after 24 months without any adjuvant therapy and without any recurrence, the patient is still doing well. This is a very rare clinical entity.

摘要

背景

隆突性皮肤纤维肉瘤(DFSP)是一种罕见的皮肤癌,起源于皮肤深层,最常见于躯干和四肢。由于其在文献中极为罕见,头皮部DFSP的病例值得记录。

病例描述

我们描述了一例41岁女性患者,其枕部出现肿物并逐渐增大。肿物为单发,大小为19×12×10厘米,有脓性分泌物和间歇性疼痛。计算机断层扫描显示枕骨中部等密度肿块,无颅内侵犯。与整形外科合作进行了肿瘤切除及游离皮瓣手术。患者术后第7天顺利出院,无任何神经功能缺损。

结论

我们的病例独特之处在于,在未接受任何辅助治疗且无任何复发的情况下,24个月后患者情况仍然良好。这是一种非常罕见的临床病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a4/11618792/66509ae5cf75/SNI-15-414-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a4/11618792/ddd96c8a4f68/SNI-15-414-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a4/11618792/5a7630ab950e/SNI-15-414-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a4/11618792/dff11e0c5b68/SNI-15-414-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a4/11618792/66509ae5cf75/SNI-15-414-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a4/11618792/ddd96c8a4f68/SNI-15-414-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a4/11618792/5a7630ab950e/SNI-15-414-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a4/11618792/dff11e0c5b68/SNI-15-414-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a4/11618792/66509ae5cf75/SNI-15-414-g004.jpg

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本文引用的文献

1
The epidemiology of dermatofibrosarcoma protuberans incidence, metastasis, and death among various population groups: A Surveillance, Epidemiology, and End Results database analysis.隆突性皮肤纤维肉瘤的流行病学:在不同人群中发病率、转移和死亡的分析:一项监测、流行病学和最终结果数据库分析。
J Am Acad Dermatol. 2024 Nov;91(5):826-833. doi: 10.1016/j.jaad.2024.05.088. Epub 2024 Jun 21.
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Dermatofibrosarcoma protuberans of the scalp: Surgical management in a multicentric series of 11 cases and systematic review of the literature.头皮隆突性皮肤纤维肉瘤:11 例多中心系列手术治疗及文献系统回顾
Surgery. 2023 Jun;173(6):1463-1475. doi: 10.1016/j.surg.2023.02.026. Epub 2023 Apr 1.
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Dermatofibrosarcoma protuberans: A clinical analysis.
隆突性皮肤纤维肉瘤:临床分析
Oncol Lett. 2018 Aug;16(2):1855-1862. doi: 10.3892/ol.2018.8802. Epub 2018 May 24.
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Recurrence case of rare scalp dermatofibrosarcoma protuberans: Two case reports of a wide radical excision, craniectomy bone involvement followed by cranioplasty and reconstruction.罕见头皮隆突性皮肤纤维肉瘤复发病例:两例广泛根治性切除、颅骨切除术伴骨受累后行颅骨成形术及重建的病例报告
Surg Neurol Int. 2017 May 26;8:82. doi: 10.4103/sni.sni_26_17. eCollection 2017.
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Incidence and Survival of Primary Dermatofibrosarcoma Protuberans in the United States.美国原发性隆突性皮肤纤维肉瘤的发病率与生存率
Dermatol Surg. 2016 Jan;42 Suppl 1:S24-31. doi: 10.1097/DSS.0000000000000300.
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A rare giant scalp dermatofibrosarcoma protuberans.一例罕见的巨大头皮隆突性皮肤纤维肉瘤。
Surg Neurol Int. 2014 Apr 1;5:45. doi: 10.4103/2152-7806.129909. eCollection 2014.
7
Dermatofibrosarcoma protuberans of the scalp with fibrosarcomatous degeneration and pulmonary metastasis.头皮隆突性皮肤纤维肉瘤伴纤维肉瘤变性及肺转移
J Clin Imaging Sci. 2011;1:55. doi: 10.4103/2156-7514.90482. Epub 2011 Dec 2.
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Management of dermatofibrosarcoma protuberans with fibrosarcomatous transformation: an evidence-based review of the literature.隆突性皮肤纤维肉瘤伴纤维肉瘤样变的治疗:文献回顾的循证评价。
J Eur Acad Dermatol Venereol. 2011 Dec;25(12):1385-91. doi: 10.1111/j.1468-3083.2011.04141.x. Epub 2011 Jun 4.
9
Current treatment options in dermatofibrosarcoma protuberans.隆突性皮肤纤维肉瘤的当前治疗选择。
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Management of scalp dermatofibrosarcoma protuberans.头皮隆突性皮肤纤维肉瘤的管理。
Dermatol Surg. 2005 Nov;31(11 Pt 1):1428-33. doi: 10.2310/6350.2005.31209.