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边缘型人格障碍患者中同性恋和双性恋取向的患病率及相关因素——一项系统综述和荟萃分析

Prevalence of homosexual and bisexual orientation in patients with borderline personality disorder and associated factors - a systematic review and meta-analysis.

作者信息

Shu Ying Chi Camille, Lau Ka To, Ho Cyrus Su Hui

机构信息

Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.

Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

出版信息

Front Psychiatry. 2024 Nov 21;15:1490157. doi: 10.3389/fpsyt.2024.1490157. eCollection 2024.

DOI:10.3389/fpsyt.2024.1490157
PMID:39640373
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11617515/
Abstract

INTRODUCTION

This meta-analysis aimed to quantitatively evaluate the association between homosexual and bisexual orientation and borderline personality disorder (BPD), including factors contributing to the association and clinical outcomes of homosexual and bisexual patients with BPD.

METHODS

We systematically searched PUBMED, PsycINFO, Cochrane Library, MEDLINE, EMBASE and Web of Science for cross-sectional or cohort studies comparing the prevalence of homosexual and bisexual orientation amongst patients with BPD and controls.

RESULTS

Our search identified 7 eligible studies, with a total sample case of 636 subjects with BPD and 535 subjects without BPD. Patients with BPD had a significantly higher likelihood of homosexual and bisexual orientation (Risk ratio [RR] 3.39, 95%CI 1.88-6.12) with a pooled prevalence of 28% (95% CI 0.24-0.31; I2 73%; 7 studies, 1171 participants). Subgroup analyses validated that BPD was independently associated with higher prevalence of both homosexual (RR 8.51, 95% CI 3.36-21.54) and bisexual orientation (RR 3.82, 95% CI 1.81-8.04), but no gender difference was yielded. Childhood sexual abuse (CSA) was associated with the development of homosexual and bisexual orientation in patients with BPD.

DISCUSSION

Poorer clinical outcomes, including physical and mental health, were associated with BPD status. Further studies are necessary to evaluate the feasibility and efficacy of sexual minority-specific treatment for these patients.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=538356, identifier CRD42024538356.

摘要

引言

本荟萃分析旨在定量评估同性恋和双性恋取向与边缘性人格障碍（BPD）之间的关联，包括导致这种关联的因素以及BPD同性恋和双性恋患者的临床结局。

方法

我们系统检索了PUBMED、PsycINFO、Cochrane图书馆、MEDLINE、EMBASE和科学网，以查找比较BPD患者与对照组中同性恋和双性恋取向患病率的横断面或队列研究。

结果

我们的检索确定了7项符合条件的研究，总样本包括636例BPD患者和535例非BPD患者。BPD患者具有同性恋和双性恋取向的可能性显著更高（风险比[RR] 3.39，95%置信区间1.88 - 6.12），合并患病率为28%（95%置信区间0.24 - 0.31；I² 73%；7项研究，1171名参与者）。亚组分析证实，BPD与同性恋（RR 8.51，95%置信区间3.36 - 21.54）和双性恋取向（RR 3.82，95%置信区间1.81 - 8.04）的较高患病率独立相关，但未产生性别差异。童年期性虐待（CSA）与BPD患者同性恋和双性恋取向的发展相关。

讨论

包括身心健康在内的较差临床结局与BPD状态相关。有必要进一步研究评估针对这些患者的性少数群体特异性治疗的可行性和有效性。

系统评价注册

https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=538356，标识符CRD42024538356。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dde/11617515/72f793da4690/fpsyt-15-1490157-g008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dde/11617515/72f793da4690/fpsyt-15-1490157-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dde/11617515/72500b637089/fpsyt-15-1490157-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dde/11617515/8a8ab3ae4ec6/fpsyt-15-1490157-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dde/11617515/c557e032cfb4/fpsyt-15-1490157-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dde/11617515/3a95b6f9382d/fpsyt-15-1490157-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dde/11617515/72f793da4690/fpsyt-15-1490157-g008.jpg

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