Ali Arif, Ullah Zakir, Ullah Rehman, Kazi Mohsin
Department of Plant Sciences, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, 45320, Pakistan.
Department of Botany, University of Peshawar, Peshawar, 25100, Pakistan.
Heliyon. 2024 Sep 28;10(20):e38669. doi: 10.1016/j.heliyon.2024.e38669. eCollection 2024 Oct 30.
Digestive issues are recognized as significant contributors to various chronic diseases, including obesity, diabetes, and cardiovascular disease. Barley, a traditional grain, offers considerable promise in addressing these health challenges due to unique nutritional and bioactive compounds.
This review examines the therapeutic potential of various parts of barley, underutilized resource, for chronic disease prevention and management.
ology: A comprehensive literature search was conducted across multiple databases like Google Scholar, PubMed, and ISI Web of Science, to identify nutritional components and functional ingredients in barley that contribute to gut health and chronic disease mitigation.
The finding suggests that humans digest barley starch more slowly than wheat and rice, which benefits chronic disease management. Barley's high-molecular-weight β-glucan high content acts as a prebiotic, promotes gut health through microbiome modulation and short-chain fatty acid production, potentially preventing colon cancer and boosting immunity. Recent studies on exploring barley grass of high land showed functional ingredients such as flavonoids, saponarin lutonarin, superoxide dismutase, gamma-aminobutyric acid, polyphenols K, Ca, Se, tryptophan chlorophyll, and vitamins, suggesting potential for enhanced antioxidant activity and improved management of chronic conditions like diabetes, cholesterol, hypertension, cardiovascular health, liver protection, and even boosted immunity.
This review underscores the therapeutic potential of barley and its components in chronic disease management, highlighting the need for well-designed clinical trials to translate these findings into effective interventions.
消化问题被认为是导致包括肥胖症、糖尿病和心血管疾病在内的各种慢性疾病的重要因素。大麦作为一种传统谷物,因其独特的营养和生物活性成分,在应对这些健康挑战方面具有很大潜力。
本综述探讨了大麦这一未充分利用的资源的各个部分在预防和管理慢性疾病方面的治疗潜力。
在谷歌学术、PubMed和科学网等多个数据库中进行了全面的文献检索,以确定大麦中有助于肠道健康和缓解慢性疾病的营养成分和功能成分。
研究结果表明,人类消化大麦淀粉的速度比小麦和大米慢,这对慢性疾病的管理有益。大麦中高分子量β-葡聚糖的高含量作为一种益生元,通过调节微生物群和产生短链脂肪酸来促进肠道健康,有可能预防结肠癌并增强免疫力。最近对高原大麦草的研究表明,其含有黄酮类化合物、皂草苷、黄木犀草素、超氧化物歧化酶、γ-氨基丁酸、多酚、钾、钙、硒、色氨酸、叶绿素和维生素等功能成分,显示出增强抗氧化活性以及改善糖尿病、胆固醇、高血压、心血管健康、肝脏保护等慢性疾病管理甚至增强免疫力的潜力。
本综述强调了大麦及其成分在慢性疾病管理中的治疗潜力,突出了开展精心设计的临床试验以将这些研究结果转化为有效干预措施的必要性。