Kıyak Veysel, Beyhan Murat, Gökçe Erkan
Faculty of Medicine, Department of Neurosurgery, Tokat Gaziosmanpasa University, Tokat, Turkey.
Faculty of Medicine, Department of Radiology, Tokat Gaziosmanpasa University, Tokat, Turkey.
Neurol Sci. 2025 Apr;46(4):1721-1732. doi: 10.1007/s10072-024-07912-y. Epub 2024 Dec 6.
Our study aimed to evaluate the incidence and anatomical locations of cerebral venous malformations (CVMs), their alterations over time, and magnetic resonance imaging (MRI) findings of their relationships with each other in patients who underwent magnetic susceptibility-weighted imaging (SWI) and contrast-enhanced MRI.
The drainage pattern of developmental venous anomalies (DVAs), the number of collecting veins, DVA thrombosis, signal-intensity abnormalities, and hemosiderin deposits (nodular, diffuse, or both) related to the DVA, were examined. The alterations over time in cavernomas (type and size) were assessed.
The study evaluated 7,826 patients who had 8,957 magnetic SWI and contrast-enhanced brain MRIs. A total of 643 CVMs were detected in 520 patients. The frequencies of DVAs, cavernomas, and capillary telangiectasias were 5.26%, 1.28%, and 0.62%, respectively. Isolated DVAs were detected in 430 (71.5%), cavernomas in 77 (12.8%), and capillary telangiectasias in 52 (8.7%) cases of CVMs. The coexistence of DVA with cavernoma and DVA with capillary telangiectasia was found in 38 (6.3%) and 4 (0.7%) cases, respectively. DVA drainage was largely provided by a single collecting vein. Signal-intensity abnormalities associated with the DVA were observed in 7, and two patients had DVA thrombosis. Hemosiderin deposits were nodular in 14 cases, diffuse in three, and both nodular and diffuse in two. In a follow-up of 11 (7.8%) cavernomas, alterations in the type and size were detected.
It is not uncommon for cavernomas to become symptomatic owing to alterations in their nature, size, and type over time, while DVAs rarely become symptomatic. Capillary telangiectasias are vascular malformations that tend to remain stable in terms of clinical and imaging features, and those with supratentorial localization are detected more frequently in the frontal lobe. On magnetic susceptibility sequences, hemosiderin deposits can be seen in the GVA region, not rarely but more frequently in nodular form, as well as in diffuse or nodular or diffuse and nodular forms.
我们的研究旨在评估接受磁敏感加权成像（SWI）和对比增强磁共振成像（MRI）的患者中脑静脉畸形（CVM）的发生率、解剖位置、随时间的变化以及它们之间关系的磁共振成像（MRI）表现。
检查发育性静脉异常（DVA）的引流模式、引流静脉数量、DVA血栓形成、信号强度异常以及与DVA相关的含铁血黄素沉积（结节状、弥漫性或两者皆有）。评估海绵状血管瘤（类型和大小）随时间的变化。
该研究评估了7826例患者，他们共进行了8957次脑部磁敏感加权成像和对比增强MRI检查。在520例患者中总共检测到643个CVM。DVA、海绵状血管瘤和毛细血管扩张症的发生率分别为5.26%、1.28%和0.62%。在CVM病例中，孤立性DVA在430例（71.5%）中被检测到，海绵状血管瘤在77例（12.8%）中被检测到，毛细血管扩张症在52例（8.7%）中被检测到。分别在38例（6.3%）和4例（0.7%）病例中发现DVA与海绵状血管瘤以及DVA与毛细血管扩张症共存。DVA引流主要由单一引流静脉提供。7例观察到与DVA相关的信号强度异常，2例患者发生DVA血栓形成。含铁血黄素沉积结节状14例，弥漫性3例，结节状和弥漫性均有2例。在对11例（7.8%）海绵状血管瘤的随访中，检测到其类型和大小发生了变化。
海绵状血管瘤由于其性质、大小和类型随时间发生变化而出现症状并不罕见，而DVA很少出现症状。毛细血管扩张症是一种血管畸形，在临床和影像学特征方面往往保持稳定，幕上定位的毛细血管扩张症在额叶中更频繁地被检测到。在磁敏感序列上，含铁血黄素沉积可见于DVA区域，并不罕见，且更常见于结节状，也可见于弥漫性或结节状与弥漫性并存的形式。
