Tsuchiya Kazuo, Nuki Tomotsugu, Tsunoda Tomo, Ito Taisuke, Mori Rie, Akashi Takuro, Oyama Yoshiyuki, Ikeda Masaki
Department of Respiratory Medicine, Shizuoka Saiseikai General Hospital, Shizuoka City, Shizuoka, Japan.
Department of Respiratory Medicine, Shizuoka Saiseikai General Hospital, Shizuoka City, Shizuoka, Japan.
Respir Investig. 2025 Jan;63(1):67-73. doi: 10.1016/j.resinv.2024.12.002. Epub 2024 Dec 5.
Coughing and other distress during bronchoscopy are undesirable for both patients and bronchoscopists. The efficacy of local anesthetics administered via aerosol sprays in the airways has been documented; however, the optimal administration method remains unclear. Furthermore, the efficacy of continuous salivary aspiration in reducing cough and other distress has not yet been evaluated.
Patients scheduled for bronchoscopy were assigned to 1 of 4 groups-group A (intrabronchial local anesthesia using a syringe without continuous oral suction); group B (intrabronchial local anesthesia using a spray catheter without continuous oral suction); group C (intrabronchial local anesthesia using a syringe with continuous oral suction using a saliva ejector); group D (intrabronchial local anesthesia using a spray catheter with continuous oral suction using a saliva ejector). The distress levels of the patients were evaluated using a questionnaire with a visual analog scale, and cough counts were quantified during bronchoscopy. Additionally, we assessed the total amount of lidocaine consumed and changes in vital signs.
Local anesthesia in the airway using a spray catheter did not reduce patient distress; however, it reduced cough frequency (P = 0.03) and lidocaine dosage (P = 0.0004). Continuous suctioning of saliva did not reduce the patients' distress or cough frequency.
The use of a spray catheter rather than a syringe is recommended for administering local anesthesia with lidocaine during bronchoscopy. Conversely, continuous suctioning of saliva is not routinely recommended for all patients.
支气管镜检查期间的咳嗽及其他不适对患者和支气管镜检查医师来说都是不理想的。经气道雾化喷雾给予局部麻醉剂的疗效已有文献记载;然而,最佳给药方法仍不明确。此外,持续唾液抽吸在减轻咳嗽及其他不适方面的疗效尚未得到评估。
计划进行支气管镜检查的患者被分为4组中的1组——A组(使用注射器进行支气管内局部麻醉,不进行持续口腔吸引);B组(使用喷雾导管进行支气管内局部麻醉,不进行持续口腔吸引);C组(使用注射器进行支气管内局部麻醉,使用唾液吸引器进行持续口腔吸引);D组(使用喷雾导管进行支气管内局部麻醉,使用唾液吸引器进行持续口腔吸引)。使用视觉模拟量表问卷评估患者的不适程度,并在支气管镜检查期间对咳嗽次数进行量化。此外,我们评估了利多卡因的总消耗量和生命体征的变化。
使用喷雾导管进行气道局部麻醉并未减轻患者的不适;然而,它降低了咳嗽频率(P = 0.03)和利多卡因剂量(P = 0.0004)。持续抽吸唾液并未减轻患者的不适或咳嗽频率。
建议在支气管镜检查期间使用喷雾导管而非注射器来给予利多卡因进行局部麻醉。相反,不常规建议对所有患者进行持续唾液抽吸。