Brinkschmidt T, Heuck C C, Schlierf G, Buchholz L, Schmidt-Gayk H
Atherosclerosis. 1986 Mar;59(3):323-8. doi: 10.1016/0021-9150(86)90128-0.
In a study of the immunoglobulin concentrations in an urban population and in patients with hyperlipoproteinemia we observed significant positive correlations between serum triglycerides and IgA independent of sex, age and body weight. In men serum triglycerides also correlated with IgG and IgM, and serum cholesterol with IgA. The prevalence of hyper- and hypoimmunoglobulinemia was significantly higher in hyperlipidemic than in normolipemic subjects. We propose that the occurrence of hyperlipoproteinemia with hypoimmunoglobulinemia may be caused by different pathobiological mechanisms than the occurrence with hyperimmunoglobulinemia.
在一项针对城市人群和高脂蛋白血症患者免疫球蛋白浓度的研究中，我们观察到血清甘油三酯与IgA之间存在显著正相关，且不受性别、年龄和体重影响。在男性中，血清甘油三酯还与IgG和IgM相关，血清胆固醇与IgA相关。高脂血症患者中高免疫球蛋白血症和低免疫球蛋白血症的患病率显著高于正常血脂受试者。我们提出，伴有低免疫球蛋白血症的高脂蛋白血症的发生机制可能与伴有高免疫球蛋白血症的情况不同。
