Stair T O, D'Orta J, Altieri M F, Lippe M S
Am J Emerg Med. 1986 May;4(3):214-7. doi: 10.1016/0735-6757(86)90068-9.
Epi-Lock, a 1-mm-thick semipermeable sheet of modified polyurethane dressing material, was compared with silver sulfadiazene cream (Silvadene) in a prospective, randomized, cross-over-controlled study in which 50 patients alternated changing antibiotic cream daily with leaving the polyurethane sheet in place for a week. Overall, patient and physician preference for Epi-Lock was statistically significant (P less than 0.004), based on less pain, easier care, and faster healing. The collection of fluid under the polyurethane dressing and the necessity of leaving the wound covered for a week were less well accepted. Epi-Lock represents a major advance in wound dressing materials and should eventually gain wide application in outpatient treatment of partial thickness burns and abrasions.
Epi-Lock是一种厚度为1毫米的改性聚氨酯半透性敷料，在一项前瞻性、随机、交叉对照研究中，将其与磺胺嘧啶银乳膏（Silvadene）进行了比较。该研究中50名患者每天交替使用抗生素乳膏，或将聚氨酯片放置一周。总体而言，基于疼痛减轻、护理简便和愈合更快，患者和医生对Epi-Lock的偏好具有统计学意义（P小于0.004）。聚氨酯敷料下积液以及伤口需覆盖一周的必要性不太容易被接受。Epi-Lock代表了伤口敷料材料的重大进步，最终应会在门诊治疗浅度烧伤和擦伤中得到广泛应用。
