Dawson K A, Crowne D P, Richardson C M
Behav Brain Res. 1986 Feb;19(2):187-90. doi: 10.1016/0166-4328(86)90018-5.
Unilateral lesions in such brain regions as medial frontal cortex and superior colliculus produce polysensory neglect contralateral to the lesion. Since the pineal gland is an unpaired brain structure, both electrophysiologically and hormonally responsive to visual and auditory stimulation, it may modulate bilateral sensory attention mechanisms. Long-Evans male rats were given pineal or sham lesions and were tested behaviourally. Sensory assessment revealed that in comparison to sham animals rats with pineal lesion exhibited unilateral visual and auditory neglect to stimuli presented on either side of the body. Animals with pineal lesions were more likely than sham-lesioned animals to demonstrate visual allesthesis and, compared to sham-lesioned rats, showed extinction on the left side to bilateral simultaneous visual stimulation. This is the first report that midline neuroendocrine damage can produce bilateral sensory inattention.
内侧额叶皮质和上丘等脑区的单侧损伤会导致损伤对侧的多感觉忽视。由于松果体是一个不成对的脑结构，在电生理和激素方面对视觉和听觉刺激都有反应，它可能会调节双侧感觉注意机制。对雄性Long-Evans大鼠进行松果体损伤或假手术，并进行行为测试。感觉评估显示，与假手术动物相比，松果体损伤的大鼠对身体两侧呈现的刺激表现出单侧视觉和听觉忽视。松果体损伤的动物比假手术动物更有可能表现出视觉异常感觉，并且与假手术大鼠相比，在双侧同时视觉刺激时左侧出现消退现象。这是中线神经内分泌损伤可导致双侧感觉注意力不集中的首次报道。
