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超重或肥胖且患有尿失禁的女性的健康相关生活质量和性功能:一项横断面研究。

Health-related quality of life and sexual function among women with overweight or obesity and urinary incontinence: a cross-sectional study.

作者信息

Tian Zhao, Wang Xiuqi, Fu Linru, Du Zhe, Lin Tangdi, Chen Wei, Sun Zhijing

机构信息

Department of Obstetrics and Gynecology, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, National Clinical Research Center for Obstetric & Gynecologic Diseases, No. 1 Shuaifu Road, Dongcheng District, Beijing, 100730, China.

Department of Clinical Nutrition, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

出版信息

Qual Life Res. 2024 Dec 7. doi: 10.1007/s11136-024-03868-w.

Abstract

PURPOSE

To assess the health related quality of life (HRQoL) and sexual function related to urinary incontinence (UI) severity among women with overweight or obesity.

METHODS

From September 2023 to January 2024, a cross-sectional was conducted among women seeking weight loss with overweight or obesity focusing on the symptoms and effects of UI. The degree of UI severity, UI-specific HRQoL, sexual function, and generic HRQoL were detected via Incontinence Modular Questionnaire-Urinary Incontinence Short Form (ICIQ-UI-SF), Incontinence Impact Questionnaire-Short Form (IIQ-7), Short-form Prolapse Incontinence Sexual Questionnaire (PISQ-12), and European Quality of Life-5 Dimensions 5-Level questionnaire (EQ-5D-5 L) respectively.

RESULTS

Out of 1205 valid responses, 564 (46.8%) reported UI with 354 classified as mild, 179 as moderate, and 31 as severe based on ICIQ-UI-SF scores. The mean age and body mass index of the respondents were 36.65 years and 29.9 kg/m², respectively. Individuals with more severe symptoms of UI exhibited correspondingly lower levels of UI-specific HRQoL, sexual function, and generic HRQoL. Although the correlations were weak, the severity of UI symptoms measured by ICIQ-UI-SF and IIQ-7 were significantly correlated with the mean utility values (r=-0.335, and - 0.351, P<0.001) of EQ-5D-5 L especially in the domains of anxiety/depression symptoms (r = 0.339 and 0.322, P<0.001).

CONCLUSION

Nearly half of women seeking weight loss with overweight or obesity may experience UI, which significantly affects HRQoL and sexual function. The severity of UI symptoms is significantly correlated with the generic HRQoL measured by EQ-5D-5 L, especially in the domain of anxiety/depression symptoms.

摘要

目的

评估超重或肥胖女性中与尿失禁(UI)严重程度相关的健康相关生活质量(HRQoL)和性功能。

方法

2023年9月至2024年1月,对寻求减肥的超重或肥胖女性进行了一项横断面研究,重点关注尿失禁的症状和影响。通过尿失禁模块化问卷-尿失禁简表(ICIQ-UI-SF)、尿失禁影响问卷-简表(IIQ-7)、简式盆腔器官脱垂尿失禁性功能问卷(PISQ-12)和欧洲生活质量-5维度5水平问卷(EQ-5D-5L)分别检测尿失禁严重程度、特定于尿失禁的HRQoL、性功能和一般HRQoL。

结果

在1205份有效回复中,564人(46.8%)报告有尿失禁,根据ICIQ-UI-SF评分,354人分类为轻度,179人为中度,31人为重度。受访者的平均年龄和体重指数分别为36.65岁和29.9kg/m²。尿失禁症状更严重的个体相应地表现出较低水平的特定于尿失禁的HRQoL、性功能和一般HRQoL。尽管相关性较弱,但ICIQ-UI-SF和IIQ-7测量的尿失禁症状严重程度与EQ-5D-5L的平均效用值(r=-0.335和-0.351,P<0.001)显著相关,尤其是在焦虑/抑郁症状领域(r=0.339和0.322,P<0.001)。

结论

近一半寻求减肥的超重或肥胖女性可能会经历尿失禁,这会显著影响HRQoL和性功能。尿失禁症状的严重程度与EQ-5D-5L测量的一般HRQoL显著相关,尤其是在焦虑/抑郁症状领域。

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