Bristol Urological Institute, Southmead Hospital, Bristol, UK.
BJU Int. 2015 Jan;115(1):143-52. doi: 10.1111/bju.12852. Epub 2014 Aug 16.
To develop a clear understanding of the relationship between severity of urinary incontinence (UI) and health-related quality of life (HRQoL) and mental well-being in a population of women of working age with the requisite demands of a busy, active life.
A survey of women with UI, aged between 45 and 60 years, was conducted via the internet in the UK, France, Germany and USA between 1 and 30 September 2013. Validated outcome measures were used to assess symptoms and the impact of UI on activities of daily life, HRQoL, and mental well-being: The International Consultation on Incontinence Modular Questionnaire Short Form; (ICIQ-UI Short Form); the ICIQ-Lower Urinary Tract Symptoms Quality of Life; (ICIQ-LUTSqol); the Warwick-Edinburgh Mental Well-being Scale (WEMWBS). The relationships between UI, HRQoL and mental well-being were analysed using analyses of variance and regression.
The survey was completed by 1203 women with UI with an average age of 52.7 years. Based upon responses to the ICIQ-UI Short Form about the amount of urine that leaks, respondents were categorised as having light (n = 1023, 87%), medium (n = 134, 11%), or severe UI (n = 20, 2%). The scores on the ICIQ-UI Short Form increased with severity [mean (sd) scores: light UI 7.9 (3.4), medium UI 13.8 (2.9), and severe UI 18.3 (3.9)], as did the impact on HRQoL, assessed using the ICIQ-LUTSqol [mean (sd) scores: light UI 30.6 (7.3), medium UI 41.0 (11.2), and severe UI 56.9 (17.6)]. Mental well-being decreased with severity of UI, the mean (se) WEMWBS scores were: light UI 48.3 (10.1), medium UI 44.5 (9.5), and severe UI 39.9 (16.2).
In women with UI, aged 45-60 years, UI symptoms directly affect HRQoL, which subsequently impacts negatively on mental well-being.
在 45 至 60 岁的有工作的女性人群中，明确了解尿失禁（UI）严重程度与生活质量（HRQoL）和心理健康之间的关系，这些女性人群具备繁忙、活跃生活所需的必要需求。
2013 年 9 月 1 日至 30 日期间，通过互联网在英国、法国、德国和美国对 45 至 60 岁的 UI 女性进行了一项调查。使用经过验证的结局测量方法来评估症状以及 UI 对日常生活活动、HRQoL 和心理健康的影响：国际尿失禁咨询问卷模块简表（ICIQ-UI 简表）；国际尿失禁咨询问卷下尿路症状生活质量简表（ICIQ-LUTSqol）；华威-爱丁堡心理健康量表（WEMWBS）。使用方差分析和回归分析来分析 UI、HRQoL 和心理健康之间的关系。
共有 1203 名 UI 女性完成了这项调查，平均年龄为 52.7 岁。根据 ICIQ-UI 简表中对漏尿量的回答，受访者被分为轻度（n = 1023，87%）、中度（n = 134，11%）或重度（n = 20，2%）UI。ICIQ-UI 简表的得分随着严重程度的增加而增加[平均（标准差）得分：轻度 UI 7.9（3.4），中度 UI 13.8（2.9），重度 UI 18.3（3.9）]，HRQoL 的影响也是如此，使用 ICIQ-LUTSqol 进行评估[平均（标准差）得分：轻度 UI 30.6（7.3），中度 UI 41.0（11.2），重度 UI 56.9（17.6）]。心理健康随着 UI 的严重程度而下降，WEMWBS 的平均（标准误）分数分别为：轻度 UI 48.3（10.1），中度 UI 44.5（9.5），重度 UI 39.9（16.2）。
在 45 至 60 岁的有 UI 的女性中，UI 症状直接影响 HRQoL，进而对心理健康产生负面影响。
