Cooper R L, Grose G C, Constable I J
Aust N Z J Ophthalmol. 1986 Feb;14(1):35-9. doi: 10.1111/j.1442-9071.1986.tb00005.x.
Because of the high false positive and negative rates for detection of suspects when screening for glaucoma by tonometry, we screened 12 156 subjects over the age of 40 years or with a stated family history of glaucoma by examining the optic discs. This was followed by Schiotz tonometry. Eight hundred and twelve (6.7%) suspects were referred to their primary physician for investigation by an ophthalmologists. A database program was used to send out follow-up letters to both suspects and ophthalmologists. Three hundred and seventy-nine replies were received from ophthalmologists: 100 (26.4%) of these suspects had ocular hypertension and 68 (17.9%) had glaucoma. Of these 68, 60 (15.8%) had chronic simple glaucoma, five (1.3%) had secondary open-angle glaucoma, and three (0.79%) had primary closed-angle glaucoma. The prevalence of all types of glaucoma in this group for which follow-up was obtained was at least 0.56% of the total number screened. Assuming that the prevalence was similar for the group for whom no replies were obtained, the prevalence of glaucoma in this population is approximately 1.19%. Screening by optic disc examination is therefore likely to detect most cases of glaucoma.
由于眼压测量法筛查青光眼可疑患者时假阳性和假阴性率较高，我们通过检查视盘对12156名40岁以上或有青光眼家族史的受试者进行了筛查。随后进行了施氏眼压测量。812名（6.7%）可疑患者被转介给他们的初级医生，由眼科医生进行检查。使用数据库程序向可疑患者和眼科医生发送随访信。收到了379名眼科医生的回复：其中100名（26.4%）可疑患者患有高眼压症，68名（17.9%）患有青光眼。在这68名患者中，60名（15.8%）患有慢性单纯性青光眼，5名（1.3%）患有继发性开角型青光眼，3名（0.79%）患有原发性闭角型青光眼。在获得随访的这组患者中，所有类型青光眼的患病率至少为筛查总数的0.56%。假设未获得回复的那组患者患病率与之相似，那么该人群中青光眼的患病率约为1.19%。因此，通过视盘检查进行筛查可能会发现大多数青光眼病例。
