Cong Han, Li Zhibiao, Zhang Jiahao, Xu Zeyao, Tang Zhicheng, Qian Yuxin, Wang Juan, Wu Haoliang, Zheng Hanxiong, He Zhaohui, Tang Fucai
Department of Urology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen 518033, China.
Department of Urology, Shantou Central Hospital, Shantou 515041, China.
J Psychosom Res. 2025 Feb;189:111999. doi: 10.1016/j.jpsychores.2024.111999. Epub 2024 Nov 28.
This research seeks to assess the connection between healthy sleep patterns and the occurrence of kidney stone disease (KSD) by analyzing data obtained from a large-scale cohort study.
We examined 313,870 initial participants without KSD from the UK Biobank. Five healthy sleep factors were assessed: no frequent excessive daytime sleepiness, early chronotype, no snoring, sleeping 7-8 h daily, and never or rarely experiencing insomnia at baseline. A healthy sleep score between 0 and 5 was assigned to participants according to these criteria. We utilized Cox proportional hazards models to calculate hazard ratios (HR) and 95 % confidence intervals (CI) between a healthy sleep score and the occurrence of KSD.
During the follow-up period, 3818 new cases of KSD were recorded. After comprehensive adjustments, every 1-point rise in the healthy sleep score was associated with an HR of 0.93 (95 % CI: 0.90-0.96). Additionally, individuals with a healthy sleep score of 5 had a 20 % lower risk of KSD compared to those with scores between 0 and 2.
Our study results indicate that adhering to a healthy sleep pattern can reduce the risk of KSD.
本研究旨在通过分析从一项大规模队列研究中获得的数据,评估健康睡眠模式与肾结石疾病(KSD)发生之间的联系。
我们对英国生物银行中313870名无KSD的初始参与者进行了检查。评估了五个健康睡眠因素:无频繁的日间过度嗜睡、早起型、无打鼾、每日睡眠7 - 8小时,以及在基线时从未或很少经历失眠。根据这些标准为参与者分配0至5的健康睡眠评分。我们使用Cox比例风险模型来计算健康睡眠评分与KSD发生之间的风险比(HR)和95%置信区间(CI)。
在随访期间,记录了3818例新的KSD病例。经过全面调整后,健康睡眠评分每升高1分,HR为0.93(95%CI:0.90 - 0.96)。此外,健康睡眠评分为5的个体与评分在0至2之间的个体相比,患KSD的风险低20%。
我们的研究结果表明,坚持健康的睡眠模式可以降低患KSD的风险。