Klaps Sim, Verbrugghe Jonas, Goossens Nina, Meus Timo, Köke Albère, Verbunt Jeanine, Langer Daniel, Timmermans Annick, Janssens Lotte
REVAL Rehabilitation Research Center, Hasselt University, Diepenbeek, Belgium.
REVAL Rehabilitation Research Center, Hasselt University, Diepenbeek, Belgium.
Respir Med. 2025 Jan;236:107887. doi: 10.1016/j.rmed.2024.107887. Epub 2024 Dec 5.
Patients with chronic nonspecific low back pain (CNSLBP) show reduced inspiratory muscle function. However, studies comparing maximal inspiratory pressure (MIP) and exercise-induced inspiratory muscle fatigue (IMF) between CNSLBP and healthy controls (HC) are lacking.
To compare MIP and exercise-induced IMF between CNSLBP and HC.
Cross-sectional study.
MIP was recorded in 25 persons with CNSLBP and 15 HC before and immediately, 15 and 30 minutes after a maximal cardiopulmonary exercise test. Inspiratory muscle weakness was defined as a predicted MIP value lower than 80%, and exercise-induced IMF as a ≥10% reduction in MIP following the exercise test.
Baseline MIP was similar between CNSLBP (109±32 cmH2O) and HC (116±32 cmH2O) (p= 0.525). Inspiratory muscle weakness was present in 36% of the CNSLBP group and in 20% of the HC group, with no significant difference between groups (p= 0.777). None of the groups showed significant exercise-induced IMF immediately (CNSLBP: -2.1%, HC: 3.7%), 15 minutes (CNSLBP: -5.4%, HC: -5.2%), and 30 minutes (CNSLBP: -4.7%, HC: -6.6%) after the maximal exercise test (p> 0.05), with no between group differences with regard to magnitude and proportion (CNSLBP: 24%, HC: 33%) (p> 0.05).
This study shows that there is no difference in MIP and the proportion of inspiratory muscle weakness between persons with CNSLBP and HC. Additionally, within both groups, there was no exercise-induced IMF immediately, 15 and 30 minutes after a maximal exercise test. Furthermore, there was no difference in the magnitude and proportion of exercise-induced IMF between both groups.
慢性非特异性下腰痛（CNSLBP）患者表现出吸气肌功能下降。然而，缺乏比较CNSLBP患者与健康对照（HC）之间最大吸气压力（MIP）和运动诱发吸气肌疲劳（IMF）的研究。
比较CNSLBP患者与HC之间的MIP和运动诱发的IMF。
横断面研究。
在25例CNSLBP患者和15例HC中，在最大心肺运动试验前、试验后即刻、15分钟和30分钟记录MIP。吸气肌无力定义为预测的MIP值低于80%，运动诱发的IMF定义为运动试验后MIP降低≥10%。
CNSLBP组（109±32 cmH2O）和HC组（116±32 cmH2O）的基线MIP相似（p = 0.525）。CNSLBP组36%的患者和HC组20%的患者存在吸气肌无力，两组之间无显著差异（p = 0.777）。在最大运动试验后即刻（CNSLBP组：-2.1%，HC组：3.7%）、15分钟（CNSLBP组：-5.4%，HC组：-5.2%）和30分钟（CNSLBP组：-4.7%，HC组：-6.6%），两组均未显示出显著的运动诱发IMF（p>0.05），两组在幅度和比例方面无组间差异（CNSLBP组：24%，HC组：33%）（p>0.05）。
本研究表明，CNSLBP患者与HC之间的MIP及吸气肌无力比例无差异。此外，在两组中，最大运动试验后即刻、15分钟和30分钟均未出现运动诱发的IMF。此外，两组之间运动诱发IMF的幅度和比例无差异。
