Lindhagen A, Bergqvist A, Bergqvist D, Hallböök T
Br J Obstet Gynaecol. 1986 Apr;93(4):348-52.
The frequency of deep venous insufficiency was investigated in 23 patients 3-10 years (mean 7 years) after they had developed an objectively diagnosed deep venous thrombosis (DVT) during pregnancy or the first week after delivery. Investigations included clinical examination, listing of symptoms and plethysmography, venous pressure and Doppler ultrasound. At follow-up there were clinical signs or symptoms of venous insufficiency in 35% of the legs with earlier DVT but in none of the non-thrombosed contralateral legs. Objective evidence of venous insufficiency was present in 15 (65%) of the legs with earlier DVT and in only five (22%) of the non-thrombosed legs. The differences between thrombosed and non-thrombosed legs are statistically significant. There was no correlation between objectively measured venous insufficiency and extent of the DVT. It is concluded that a DVT during pregnancy often leads to venous insufficiency and the risk seems to be higher than after DVT occurring in other groups of patients.
对23例在孕期或产后第一周发生客观诊断的深静脉血栓形成（DVT）3至10年（平均7年）后的患者进行了深静脉功能不全发生率的调查。调查包括临床检查、症状记录以及体积描记法、静脉压测量和多普勒超声检查。随访时，早期发生DVT的腿部有35%出现静脉功能不全的临床体征或症状，而对侧未发生血栓形成的腿部均未出现。早期发生DVT的腿部中有15条（65%）存在静脉功能不全的客观证据，而未发生血栓形成的腿部中只有5条（22%）存在该证据。发生血栓形成的腿部与未发生血栓形成的腿部之间的差异具有统计学意义。客观测量的静脉功能不全与DVT的范围之间无相关性。结论是孕期发生的DVT常导致静脉功能不全，且该风险似乎高于其他患者群体发生DVT后的风险。
