Hui S W, Huang C H
Biochemistry. 1986 Mar 25;25(6):1330-5. doi: 10.1021/bi00354a021.
X-ray diffraction experiments have been performed on 1-stearoyllysophosphatidylcholine or C(18):C(0)PC as a function of hydration at temperatures below the order/disorder transition (Tm = 26.2 degrees C). At these temperatures, hydrated C(18):C(0)PC forms lamellae. The bilayer thickness, as determined by the saturation hydration method and electron-density profile, is 35-36 A, and the average area per C(18):C(0)PC molecule at the lipid/water interface is 45.5 A2. The packing geometry of C(18):C(0)PC in the lamella is proposed to adopt a fully interdigitated model in which the long C(18) acyl chain extends across the entire hydrocarbon width of the bilayer. Thus far, three different types of interdigitated bilayers are known for phosphatidylcholines. These various types of chain interdigitation are discussed in terms of the chain length difference between the sn-1 and sn-2 acyl chains.
已对1-硬脂酰溶血磷脂酰胆碱或C(18):C(0)PC在低于有序/无序转变温度（Tm = 26.2摄氏度）时作为水合作用的函数进行了X射线衍射实验。在这些温度下，水合的C(18):C(0)PC形成片层。通过饱和水合法和电子密度分布确定的双层厚度为35 - 36埃，并且在脂质/水界面处每个C(18):C(0)PC分子的平均面积为45.5埃²。提出C(18):C(0)PC在片层中的堆积几何结构采用完全交错模型，其中长的C(18)酰基链延伸穿过双层的整个烃宽度。到目前为止，已知磷脂酰胆碱有三种不同类型的交错双层。根据sn-1和sn-2酰基链之间的链长差异讨论了这些不同类型的链交错。
