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[造血干细胞移植的保护环境策略:进展与展望]

[Protective environment strategies for hematopoietic stem cell transplantation: progress and prospects].

作者信息

Zhou Xiaoyu, Zhang Jianli, Xu Liwei, Jin Aiyun

机构信息

Nursing Department, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

出版信息

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2024 Dec 25;53(6):796-803. doi: 10.3724/zdxbyxb-2024-0082.

Abstract

With the progress of hematopoietic stem cell transplantation technology, the reduction of pretreatment intensity, the shortening of bone marrow suppression time and the reduction of infection risk, especially the physical and psychological stress for doctors and patients caused by rigorous protection procedures, the protective environment strategies need improvement. It has been found that, regardless of whether total environment protection is implemented, there is no significant difference in the outcomes of chemotherapy patients with neutropenia. Therefore, the traditional protective environment strategies are being improved. The protective environment strategies for hematopoietic stem cell transplantation patients have developed rapidly in the past two decades, from the replacement of laminar flow equipment by high-efficiency filtration devices to the development of home care after transplantation. In this article, the progress in protective environment strategies for hematopoietic stem cell transplantation patients is reviewed and further reflect, providing reference for future improvement.

摘要

随着造血干细胞移植技术的进步、预处理强度的降低、骨髓抑制时间的缩短以及感染风险的降低,特别是严格的防护措施给医生和患者带来的身心压力,保护性环境策略需要改进。研究发现,无论是否实施全面环境保护,中性粒细胞减少的化疗患者的治疗结果并无显著差异。因此,传统的保护性环境策略正在改进。在过去二十年中,造血干细胞移植患者的保护性环境策略发展迅速,从用高效过滤装置取代层流设备到移植后家庭护理的发展。本文回顾并进一步思考了造血干细胞移植患者保护性环境策略的进展,为未来的改进提供参考。

相似文献

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[Allogeneic hematopoietic stem cell transplantations].[异基因造血干细胞移植]
Transfus Clin Biol. 2011 Apr;18(2):235-45. doi: 10.1016/j.tracli.2011.02.021. Epub 2011 Apr 3.

本文引用的文献

1
Safe design and maintenance of bone marrow transplant units: a narrative review.骨髓移植单位的安全设计与维护:叙述性评论。
Clin Microbiol Infect. 2022 Aug;28(8):1091-1096. doi: 10.1016/j.cmi.2022.03.032. Epub 2022 Apr 2.

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