Kuryltsiv Nadiia, Zborovska Oleksandra, Velychko Liudmyla, Bohdanova Aleksandra
Cesk Slov Oftalmol. 2025;81(3):141-148. doi: 10.31348/2024/44.
to investigate the dynamics of the T-cell immune response in rabbits with experimental autoimmune uveitis (EAU) of varying severity.
The experiment involved two groups of Chinchilla rabbits (15 rabbits in each group). The model of EAU was created. The clinical picture of intraocular inflammation of varying severity was assessed. The determination of the level of white blood cells (WBC), lymphocytes (Lymphs), CD3+, CD4+, CD8+, and CD16+ in the blood of rabbits was conducted.
Group I - moderate and severe uveitis, Group II - uveitis of mild severity. WBC, Lymphs, CD3+, CD4+, CD16+ were elevated and statistically significant in both groups of animals compared to control parameters on all days of the experiment (3, 7, 10, 14, 21 days) (p.
研究不同严重程度实验性自身免疫性葡萄膜炎（EAU）家兔的T细胞免疫反应动态变化。
实验涉及两组青紫蓝兔（每组15只）。建立EAU模型。评估不同严重程度的眼内炎症临床表现。测定家兔血液中白细胞（WBC）、淋巴细胞（Lymphs）、CD3 +、CD4 +、CD8 +和CD16 +水平。
第一组——中度和重度葡萄膜炎，第二组——轻度葡萄膜炎。在实验的所有天数（第3、7、10、14、21天），与对照参数相比，两组动物的WBC、Lymphs、CD3 +、CD4 +、CD16 +均升高且具有统计学意义（p值……此处原文未完整给出）
