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脂肪脊髓脊膜膨出的治疗。多伦多病童医院的经验。

Management of lipomyelomeningoceles. Experience at the Hospital for Sick Children, Toronto.

作者信息

Hoffman H J, Taecholarn C, Hendrick E B, Humphreys R P

出版信息

J Neurosurg. 1985 Jan;62(1):1-8. doi: 10.3171/jns.1985.62.1.0001.

Abstract

Ninety-seven children with lipomyelomeningoceles were operated on at the Hospital for Sick Children between January, 1960, and December, 1982. The most common factor that caused these patients to seek help was the cosmetic effect of the mass on their back. However, 22 patients had urinary incontinence and 15 patients had a deformed or weak leg. Sixty of the 97 patients were female and 37 were male. The patients presented for treatment between 6 days and 18 1/2 years of age with a median age of 7 1/2 months. Fifty-six patients presented before the age of 6 months and 35 of these were perfectly normal at the time of presentation. On the other hand, of the 41 patients who were brought for treatment after the age of 6 months, only 12 were normal prior to surgery. When patients were appropriately treated at an early age, with their spinal cords untethered and their dura securely closed with a dural graft, then they remained unchanged neurologically or even improved. However, when treatment was delayed or not done appropriately then they were left with significant neurological sequelae. Lipomyelomeningoceles are serious lesions which without appropriate therapy can result in gross impairment of neurological function.

摘要

1960年1月至1982年12月期间,97名患有脂肪脊髓脊膜膨出的儿童在病童医院接受了手术。这些患者寻求帮助的最常见原因是背部肿块的外观影响。然而,22名患者有尿失禁,15名患者腿部畸形或无力。97名患者中60名是女性,37名是男性。患者就诊时年龄在6天至18岁半之间,中位年龄为7个半月。56名患者在6个月龄之前就诊,其中35名在就诊时完全正常。另一方面,在6个月龄之后前来治疗的41名患者中,只有12名在手术前是正常的。如果患者在幼年时得到适当治疗,脊髓松解,硬脑膜用硬脑膜移植物牢固闭合,那么他们的神经功能保持不变甚至有所改善。然而,如果治疗延迟或不适当,那么他们会留下严重的神经后遗症。脂肪脊髓脊膜膨出是严重的病变,未经适当治疗可导致神经功能严重受损。

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