Ngoubangoye Barthélémy, Dibakou Serge-Ely, Otsaghe Ekore Désiré, Tsoumbou Thierry Audrey Gaël, Moussadji Kinga Ivan Cyr, Yanagha Freddy, Okomo Nguema Linaa Yasmine, Boudenga Larson, Pontier Dominique
Centre de Primatologie, Centre Interdisciplinaire de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon.
LabEx ECOFECT, Eco-evolutionary Dynamics of Infectious Diseases, University of Lyon, Lyon, France.
Am J Primatol. 2025 Jan;87(1):e23703. doi: 10.1002/ajp.23703.
This study aimed to establish a baseline hematological profile and examine the influence of age, sex, and season on hematological parameters in captive chimpanzees (Pan troglodytes) living in a humid tropical climate. Hematological parameters are a useful tool for assessing health status and diagnosing diseases in animals. We analyzed 473 blood samples collected from 84 chimpanzees (43 females and 41 males) during annual health checks, conducted under anesthesia for a routine physical examination. The main findings revealed significant sex differences in some hematological parameters: males had higher hematocrit and red blood cell counts than females. Age-related variations have also been noted, with adolescents and adults having lower lymphocyte counts but higher neutrophil and monocyte counts than infants. Adults, in particular, had significantly lower platelet counts compared to other age classes. Seasonal fluctuations were also observed: lymphocyte counts were higher in the rainy season, while neutrophil counts were higher in the dry season. In addition, the general trends in hematological parameters for this captive population of chimpanzees were similar to those reported in captive chimpanzees living in the United States. These results should provide animal health professionals, particularly those working with nonhuman primates, with data to compare and interpret. They will help improve practices for monitoring and managing the health of nonhuman primates in captivity.
本研究旨在建立圈养黑猩猩（Pan troglodytes）的血液学基线资料，并考察年龄、性别和季节对生活在潮湿热带气候中的圈养黑猩猩血液学参数的影响。血液学参数是评估动物健康状况和诊断疾病的有用工具。我们分析了在年度健康检查期间从84只黑猩猩（43只雌性和41只雄性）采集的473份血液样本，这些检查是在麻醉下进行的常规体格检查。主要研究结果显示，某些血液学参数存在显著的性别差异：雄性的血细胞比容和红细胞计数高于雌性。还注意到与年龄相关的差异，青少年和成年黑猩猩的淋巴细胞计数低于婴儿，但中性粒细胞和单核细胞计数高于婴儿。特别是，成年黑猩猩的血小板计数明显低于其他年龄组。还观察到季节性波动：雨季淋巴细胞计数较高，旱季中性粒细胞计数较高。此外，这群圈养黑猩猩的血液学参数总体趋势与生活在美国的圈养黑猩猩报告的趋势相似。这些结果应为动物健康专业人员，特别是从事非人灵长类动物工作的人员，提供可比较和解释的数据。它们将有助于改进圈养非人灵长类动物健康监测和管理的做法。
