Suppr超能文献

重新评估女性静脉血栓栓塞(VTE)事件的风险

Reassessing the Risk of Venous Thromboembolism (VTE) Events in Women.

作者信息

He Changhuai, Chu Jie, Li Yiqing, Dang Yiping, Xue Kaming, Cai Chuanqi

机构信息

Department of Hepatobiliary Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, China.

Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Clin Appl Thromb Hemost. 2024 Jan-Dec;30:10760296241305108. doi: 10.1177/10760296241305108.

Abstract

This research aims to reassess women's risk of venous thromboembolism (VTE) events. We conducted an in-depth analysis of the environmental risk factors associated with VTE and their interactions with gender while also exploring the genetic underpinnings of the disease. VTE is identified as a multifactorial condition influenced by a combination of genetic, non-predisposing, and predisposing environmental factors. We further investigated the genetic basis of VTE, focusing on the identification and analysis of risk loci, as well as gene interaction networks and genetic analyses, which offer significant insights into the pathogenesis of VTE. Recognizing the critical role of gender in assessing VTE risk and developing prevention strategies, this research underscores the necessity of adopting an integrated perspective that accounts for individual vulnerabilities at both genetic and environmental levels to formulate effective preventive measures.

摘要

本研究旨在重新评估女性发生静脉血栓栓塞(VTE)事件的风险。我们对与VTE相关的环境风险因素及其与性别的相互作用进行了深入分析,同时也探索了该疾病的遗传基础。VTE被确定为一种受遗传、非易感性和易感性环境因素综合影响的多因素疾病。我们进一步研究了VTE的遗传基础,重点是风险位点的识别与分析,以及基因相互作用网络和遗传分析,这些为深入了解VTE的发病机制提供了重要见解。鉴于性别在评估VTE风险和制定预防策略中的关键作用,本研究强调有必要采取综合视角,在遗传和环境层面考虑个体易感性,以制定有效的预防措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/249f/11626654/1697797aa06c/10.1177_10760296241305108-fig1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验