• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

老年胃癌患者术前营养不良与根治性胃切除术后的不良预后

Preoperative malnutrition in elderly gastric cancer patients and adverse postoperative outcomes of radical gastrectomy.

作者信息

Liu Shan-Shan, Wang Liang

机构信息

Department of Gastrointestinal Oncology Surgery, The Affiliated Hospital of Qinghai University, Xi'ning 810000, Qinghai Province, China.

出版信息

World J Gastrointest Surg. 2024 Nov 27;16(11):3618-3622. doi: 10.4240/wjgs.v16.i11.3618.

DOI:10.4240/wjgs.v16.i11.3618
PMID:39649194
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11622084/
Abstract

Malnutrition is not only a prevalent condition among the elderly but also a common comorbidity in elderly people with gastric cancer (GC). Malnutrition is closely linked to high rates of postoperative complications and poor wound healing in elderly GC patients, which may lead to a higher incidence and mortality rate of GC. Malnutrition decreases the physical function of elderly GC patients after surgery, severely affecting their postoperative life quality and hindering subsequent treatments. This retrospective study was conducted by Zhao , focusing on the clinical baseline data, postoperative complications, and hospitalization times of elderly GC patients who underwent curative gastrectomy. Additionally, the underlying causes of poor outcomes for patients were discussed. This study may provide a solid basis for the clinical treatment of elderly GC patients in the future. Therefore, malnutrition can serve as a negative prognostic factor for curative surgery in GC patients. Addressing malnutrition and its adverse effects can benefit elderly GC patients from surgical treatment.

摘要

营养不良不仅在老年人中普遍存在,也是老年胃癌(GC)患者常见的合并症。营养不良与老年GC患者术后并发症发生率高及伤口愈合不良密切相关,这可能导致GC的发病率和死亡率升高。营养不良会降低老年GC患者术后的身体功能,严重影响其术后生活质量并阻碍后续治疗。这项回顾性研究由赵进行,重点关注接受根治性胃切除术的老年GC患者的临床基线数据、术后并发症及住院时间。此外,还讨论了患者预后不良的潜在原因。本研究可能为未来老年GC患者的临床治疗提供坚实依据。因此,营养不良可作为GC患者根治性手术的不良预后因素。解决营养不良及其不良影响可使老年GC患者从手术治疗中获益。

相似文献

1
Preoperative malnutrition in elderly gastric cancer patients and adverse postoperative outcomes of radical gastrectomy.老年胃癌患者术前营养不良与根治性胃切除术后的不良预后
World J Gastrointest Surg. 2024 Nov 27;16(11):3618-3622. doi: 10.4240/wjgs.v16.i11.3618.
2
Dismal prognosis of elderly gastric cancer patients who underwent gastrectomy with American Society of Anesthesiologists (ASA) 3.行根治性胃切除术的老年胃癌患者美国麻醉医师协会(ASA)分级 3 级的预后不良。
Langenbecks Arch Surg. 2022 Dec;407(8):3413-3421. doi: 10.1007/s00423-022-02672-9. Epub 2022 Sep 6.
3
Clinical significance of preoperative nutritional status in elderly gastric cancer patients undergoing radical gastrectomy: A single-center retrospective study.老年胃癌患者根治性胃切除术前营养状况的临床意义:一项单中心回顾性研究。
World J Gastrointest Surg. 2024 Jul 27;16(7):2211-2220. doi: 10.4240/wjgs.v16.i7.2211.
4
Prognostic Significance of Preoperative Nutritional Assessment in Elderly Patients who Underwent Laparoscopic Gastrectomy for Stage I-III Gastric Cancer.术前营养评估对行腹腔镜胃癌根治术的Ⅰ-Ⅲ期老年胃癌患者的预后意义。
Anticancer Res. 2023 Feb;43(2):893-901. doi: 10.21873/anticanres.16232.
5
The CONUT Score Can Predict the Prognosis of Gastric Cancer Patients After Curative Treatment.CONUT评分可预测胃癌患者根治性治疗后的预后。
Anticancer Res. 2025 Mar;45(3):1251-1260. doi: 10.21873/anticanres.17512.
6
The Preoperative Geriatric Nutritional Risk Index Predicts Postoperative Complications in Elderly Patients with Gastric Cancer Undergoing Gastrectomy.术前老年营养风险指数可预测老年胃癌患者胃切除术后的并发症。
In Vivo. 2018 Nov-Dec;32(6):1667-1672. doi: 10.21873/invivo.11430.
7
Curative surgery for gastric cancer in the elderly: treatment decisions, surgical morbidity, mortality, prognosis and quality of life.老年胃癌的根治性手术:治疗决策、手术并发症、死亡率、预后及生活质量
Tumori. 2007 Sep-Oct;93(5):478-84. doi: 10.1177/030089160709300512.
8
Prognostic value of 11-factor modified frailty index in postoperative adverse outcomes of elderly gastric cancer patients in China.11项因素改良衰弱指数对中国老年胃癌患者术后不良结局的预后价值
World J Gastrointest Surg. 2023 Jun 27;15(6):1093-1103. doi: 10.4240/wjgs.v15.i6.1093.
9
Visceral Adipose Tissue Assessment Enhances the Prognostic Value of GLIM Criteria in Patients with Gastric Cancer Undergoing Radical Gastrectomy after Neoadjuvant Treatment.内脏脂肪组织评估增强了新辅助治疗后接受根治性胃切除术的胃癌患者 GLIM 标准的预后价值。
Nutrients. 2022 Nov 27;14(23):5047. doi: 10.3390/nu14235047.
10
The relationship between the GLIM-defined malnutrition, body composition and functional parameters, and clinical outcomes in elderly patients undergoing radical gastrectomy for gastric cancer.GLIM 定义的营养不良与老年胃癌根治术患者的身体成分和功能参数及临床结局的关系。
Eur J Surg Oncol. 2021 Sep;47(9):2323-2331. doi: 10.1016/j.ejso.2021.02.032. Epub 2021 Mar 6.

引用本文的文献

1
Urinary Titin on the First Postoperative Day Predicts Long-Term Skeletal Muscle Loss in Patients with Gastroenterological Cancer.术后第一天的尿肌联蛋白可预测胃肠癌患者的长期骨骼肌丢失。
Int J Mol Sci. 2025 Feb 26;26(5):2026. doi: 10.3390/ijms26052026.

本文引用的文献

1
Clinical significance of preoperative nutritional status in elderly gastric cancer patients undergoing radical gastrectomy: A single-center retrospective study.老年胃癌患者根治性胃切除术前营养状况的临床意义:一项单中心回顾性研究。
World J Gastrointest Surg. 2024 Jul 27;16(7):2211-2220. doi: 10.4240/wjgs.v16.i7.2211.
2
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.2022 年全球癌症统计数据:全球 185 个国家和地区 36 种癌症的发病率和死亡率全球估计数。
CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322/caac.21834. Epub 2024 Apr 4.
3
Prognostic value of GLIM-defined malnutrition in combination with hand-grip strength or gait speed for the prediction of postoperative outcomes in gastric cancer patients with cachexia.GLIM 定义的营养不良与握力或步速联合预测合并恶液质的胃癌患者术后结局的预后价值。
BMC Cancer. 2024 Feb 23;24(1):253. doi: 10.1186/s12885-024-11880-z.
4
National and subnational trends in cancer burden in China, 2005-20: an analysis of national mortality surveillance data.中国 2005-20 年的癌症负担的国家和省级趋势:基于国家死亡率监测数据的分析。
Lancet Public Health. 2023 Dec;8(12):e943-e955. doi: 10.1016/S2468-2667(23)00211-6.
5
Preoperative low muscle mass and malnutrition affect the clinical prognosis of locally advanced gastric cancer patients undergoing radical surgery.术前低肌肉量和营养不良影响接受根治性手术的局部晚期胃癌患者的临床预后。
Front Oncol. 2023 Apr 26;13:1156359. doi: 10.3389/fonc.2023.1156359. eCollection 2023.
6
Malnutrition in older adults.老年人营养不良
Lancet. 2023 Mar 18;401(10380):951-966. doi: 10.1016/S0140-6736(22)02612-5. Epub 2023 Jan 27.
7
GLIM-defined malnutrition and overall survival in cancer patients: A meta-analysis.GLIM 定义的营养不良与癌症患者的总生存:一项荟萃分析。
JPEN J Parenter Enteral Nutr. 2023 Feb;47(2):207-219. doi: 10.1002/jpen.2463. Epub 2022 Dec 7.
8
Coexistence of GLIM-defined malnutrition and sarcopenia have negative effect on the clinical outcomes in the elderly gastric cancer patients after radical gastrectomy.GLIM定义的营养不良与肌肉减少症并存对老年胃癌患者根治性胃切除术后的临床结局有负面影响。
Front Nutr. 2022 Aug 19;9:960670. doi: 10.3389/fnut.2022.960670. eCollection 2022.
9
Correlation Between Components of Malnutrition Diagnosed by Global Leadership Initiative on Malnutrition Criteria and the Clinical Outcomes in Gastric Cancer Patients: A Propensity Score Matching Analysis.基于全球营养不良领导倡议标准诊断的营养不良成分与胃癌患者临床结局的相关性:倾向评分匹配分析
Front Oncol. 2022 Mar 3;12:851091. doi: 10.3389/fonc.2022.851091. eCollection 2022.
10
Cancer statistics in China and United States, 2022: profiles, trends, and determinants.中国和美国 2022 年癌症统计数据:概况、趋势和决定因素。
Chin Med J (Engl). 2022 Feb 9;135(5):584-590. doi: 10.1097/CM9.0000000000002108.