Caprioli Lucia, Parisi Francesca, Caprioli Lisa, Massaro Maria, Buracco Paolo, Dilli Noemi, Borgonovo Simone, Abramo Francesca
Clinica Veterinaria Arenzano, Arenzano Genoa, Italy.
Department of Veterinary Sciences, Pisa, Italy.
JFMS Open Rep. 2024 Dec 7;10(2):20551169241277090. doi: 10.1177/20551169241277090. eCollection 2024 Jul-Dec.
Ectopic thyroid tissue is rarely reported in dogs and cats in its prediaphragmatic location and has never been described in the liver. A 15-year-old spayed female domestic shorthair cat was diagnosed by ultrasound with a heterogeneous hypoechoic nodular area in the liver at the periphery of the quadrate lobe. A generic diagnosis of carcinoma was made after ultrasound-guided fine-needle aspiration and cytological examination. The patient underwent staging by CT scan and subsequently underwent hepatic lobectomy. Histologically, a diagnosis of thyroid adenocarcinoma was made, confirmed immunohistochemically using positive thyroglobulin staining; the tumour was suspected to be of metastatic origin. CT scans excluded primary thyroid involvement; in addition, lesions at other sites were not detected. Therefore, a final diagnosis of thyroid adenocarcinoma arising from ectopic thyroid tissue in the liver was made. The cat recovered uneventfully from surgery.
This report describes an unusual case of an adenocarcinoma originating from presumed thyroid ectopic tissue within the liver of a cat. Ectopic thyroid tissue has been rarely reported in both dogs and cats and, to the authors' knowledge, it has never been described in the liver of a cat.
异位甲状腺组织在犬猫的膈前位置很少见报道，且从未在肝脏中被描述过。一只15岁已绝育的雌性家猫经超声诊断，在方形叶周边的肝脏中有一个异质性低回声结节区域。在超声引导下细针穿刺和细胞学检查后做出了癌的初步诊断。患者接受了CT扫描分期，随后接受了肝叶切除术。组织学上，诊断为甲状腺腺癌，通过甲状腺球蛋白阳性染色免疫组化得以证实；怀疑肿瘤为转移起源。CT扫描排除了原发性甲状腺受累；此外，未检测到其他部位的病变。因此，最终诊断为肝脏中异位甲状腺组织起源的甲状腺腺癌。这只猫术后恢复顺利。
本报告描述了一例罕见病例，一只猫的肝脏中推测为甲状腺异位组织起源的腺癌。异位甲状腺组织在犬猫中均很少见报道，据作者所知，从未在猫的肝脏中被描述过。
