Navyadevi Undavalli, Ganni Sadhika, Satya Saka, Konala Subhashini, Kolalapudi Seetharam Anjaneyulu, Chilka Surya Prasad, Anargha Bommareddy
Department of Dermatology, Venereology, and Leprosy, GSL Medical College, Rajahmahendravaram, Andhra Pradesh, India.
J Cutan Aesthet Surg. 2024 Oct-Dec;17(4):315-319. doi: 10.25259/jcas_175_23. Epub 2024 Sep 27.
To study the efficacy and safety of microneedling radiofrequency (MNRF) in the treatment of acne scars.
This is a hospital-based and prospective interventional study. A total of 44 patients (18- 55 years old), skin types III-V, with acne scars, were enrolled. Four sessions of MNRF (Lumenis legend PRO Machine, with non-insulated needle tips GEN6, GEN6L; Israel) were done with an interval of 3 weeks between each session and followed up 1 month after the last session. The outcome was assessed by Goodman and Baron's qualitative and quantitative acne scar grading, physician global assessment (PGA), and patient satisfaction score (PSS).
Out of 44 patients, four patients could not complete the study. Goodman and Baron's qualitative assessment showed patients with Grades 2, 3, and 4 were 6 (15%), 17 (42.5%), and 17 (42.5%), respectively. At the end of follow-up, patients with Grades 1, 2, 4, and 4 acne scars were 5 (12.5%), 24 (60%), 10 (25%), and 1 (2.5%), respectively, which were statistically significant ( < 0.05). Seven patients showed no improvement. Goodman and Baron's quantitative assessment showed an initial mean of 12.65 and an after-follow-up mean of 8.3, which was statistically significant < 0.05). PGA and PSS scores showed excellent to good responses of 70% and 82.5%, respectively. Adverse effects such as post-treatment erythema were seen in all patients, and edema was observed in 12 patients. Post-inflammatory hyperpigmentation was noted in two patients.
MNRF was found to be effective with a better safety profile for acne scars.
研究微针射频（MNRF）治疗痤疮瘢痕的疗效和安全性。
这是一项基于医院的前瞻性干预研究。共纳入44例年龄在18至55岁、皮肤类型为III - V型且患有痤疮瘢痕的患者。进行了4次微针射频治疗（以色列Lumenis legend PRO机器，使用非绝缘针头GEN6、GEN6L），每次治疗间隔3周，并在最后一次治疗后随访1个月。通过古德曼和巴伦的定性和定量痤疮瘢痕分级、医生整体评估（PGA）以及患者满意度评分（PSS）来评估结果。
44例患者中，4例患者未能完成研究。古德曼和巴伦的定性评估显示，2级、3级和4级患者分别有6例（15%）、17例（42.5%）和17例（42.5%）。随访结束时，1级、2级、3级和4级痤疮瘢痕患者分别为5例（12.5%）、24例（60%）、10例（25%）和1例（2.5%），差异具有统计学意义（P < 0.05）。7例患者无改善。古德曼和巴伦的定量评估显示，初始平均分为12.65，随访后平均分为8.3，差异具有统计学意义（P < 0.05）。PGA和PSS评分显示，分别有70%和82.5%的患者反应良好。所有患者均出现治疗后红斑等不良反应，12例患者出现水肿。2例患者出现炎症后色素沉着。
发现微针射频治疗痤疮瘢痕有效且安全性较好。
