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雄激素性脱发中毛囊镜检查结果与严重程度的相关性

Correlation of Trichoscopic Findings with Severity in Androgenetic Alopecia.

作者信息

Murali Savitha, Rajamohanan Remya Raj, Kuruvila Sheela

机构信息

From the Department of Dermatology, St. John's Medical College and Hospital, Bengaluru, Karnataka, India.

Department of Dermatology, Indira Gandhi Medical College and Research Institute, Pondicherry, India.

出版信息

Indian J Dermatol. 2024 Sep-Oct;69(5):422. doi: 10.4103/ijd.ijd_349_24. Epub 2024 Oct 29.

Abstract

BACKGROUND

Androgenetic Alopecia (AGA) refers to the appearance of common non-scarring progressive loss of terminal hair. Trichoscopy shows a magnified view of the hair shafts and hair follicle openings and helps us to diagnose, prognosticate and determine the disease severity.

AIMS

The aim of the study was to identify the trichoscopic findings in patients with androgenetic alopecia and associate these findings with disease severity.

METHODS

This was a cross-sectional analytical study of both male and female patients with AGA. The Hamilton Norwood staging was used in males and Ludwig's staging was used in females. The NC 2 Heine Dermoscope was used to assess the scalp and a 64 MP rear camera was used for the photographic assessment. A Chi-square test was performed to find out the association between the stage of alopecia and trichoscopic findings.

RESULTS

A total of 63 patients were assessed in this study. Trichoscopic examination showed Hair Shaft Heterogeneity (HSTH) in all patients of AGA. Scalp honeycomb pigmentation and brown peripilar signs were seen in more than half of the patients. The white peripilar sign was associated with advanced stages in both male and female patients, ( = 0.015) and ( = 0.038) respectively. Focal atrichia was also associated with advanced stages in both male and female patients, ( = 0.001) and ( = 0.05) respectively.

CONCLUSION

HSTH was the characteristic trichoscopic feature of AGA. White peripilar sign and focal atrichia correlated with the severity of the disease. Trichoscopy-based assessment can be used to individualise the treatment options and counsel the patients regarding prognosis.

摘要

背景

雄激素性脱发(AGA)是指常见的非瘢痕性终末期毛发进行性脱落。毛发镜可放大观察毛干和毛囊开口,有助于我们进行诊断、预测和确定疾病严重程度。

目的

本研究旨在确定雄激素性脱发患者的毛发镜检查结果,并将这些结果与疾病严重程度相关联。

方法

这是一项对男性和女性AGA患者的横断面分析研究。男性采用汉密尔顿-诺伍德分期,女性采用路德维希分期。使用NC 2海涅皮肤镜评估头皮,并用6400万像素后置摄像头进行摄影评估。进行卡方检验以找出脱发分期与毛发镜检查结果之间的关联。

结果

本研究共评估了63例患者。毛发镜检查显示所有AGA患者均有毛干异质性(HSTH)。超过一半的患者出现头皮蜂窝状色素沉着和棕色毛囊周征。白色毛囊周征在男性和女性患者中均与晚期相关,分别为(P = 0.015)和(P = 0.038)。局灶性脱发在男性和女性患者中也与晚期相关,分别为(P = 0.001)和(P = 0.05)。

结论

HSTH是AGA的特征性毛发镜表现。白色毛囊周征和局灶性脱发与疾病严重程度相关。基于毛发镜的评估可用于个性化治疗方案,并就预后向患者提供咨询。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ad0/11623408/9a49a522a92b/IJD-69-422b-g001.jpg

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