Department of Dermatovenereology, University Clinical Center Sarajevo, Bosnia and Herzegovina.
Med Arch. 2021 Apr;75(2):109-111. doi: 10.5455/medarh.2021.75.109-111.
Androgenetic alopecia (AGA) is an androgen-related condition that develops in genetically predisposed individuals. The condition is characterized by the progressive loss of terminal hairs on the scalp in a characteristic distribution. Trichoscopy represents the dermoscopy imaging of the scalp and hair. Structures which may be visualized by trichoscopy include hair shafts, hair follicle openings, perifollicular epidermis and cutaneous microvessels.
The aim of this prospective study was to identify the trichoscopic features of androgenetic alopecia.
Hundred-four patients with AGA and 80 healthy subjects were enrolled in this study. Data on age, gender, personal and family history, clinical type and duration of disease were collected and analyzed. Control group consisted of 80 generally healthy subjects. Trichoscopic examination was performed using either videodermatoscope or handheld dermatoskope. Trichoscopy results were obtained in frontal, occipital and both temporal areas of the scalp, including number of yellow dots and vellus hairs, number of hairs in one pilosebaceous unit and percentage of follicular ostia with perifollicular hyperpigmentation. The data were statistically evaluated.
The number of yellow dots, pilosebaceous units with only one hair and with perifollicular hyperpigmentation was significantly increased in androgenetic alopecia (p<0.05). The percentage of thin hairs (<0.03 mm) in AGA was significantly higher than in healthy controls (p<0.05).
Our study has shown the significances of trichoscopy of patients with AGA. Regular clinical and trichoscopical follow-ups are very important to monitor disease activity and treatment tolerance.
雄激素性脱发(AGA)是一种与雄激素相关的疾病,发生在遗传易感性个体中。该疾病的特征是头皮上的终末毛发逐渐丢失,呈特征性分布。毛发镜检查代表头皮和头发的皮肤镜成像。通过毛发镜检查可以观察到的结构包括毛发轴、毛囊开口、毛囊周围表皮和皮肤微血管。
本前瞻性研究旨在确定雄激素性脱发的毛发镜特征。
本研究纳入了 104 例 AGA 患者和 80 例健康对照者。收集并分析了年龄、性别、个人和家族史、临床类型和疾病持续时间等数据。对照组由 80 名一般健康受试者组成。使用视频皮肤镜或手持皮肤镜对头顶部、后枕部和两侧颞部的头皮进行毛发镜检查。记录黄色点的数量、毳毛数量、一个毛囊单位中头发的数量以及滤泡周围色素沉着的毛囊开口百分比。对这些结果进行统计学评估。
AGA 患者的黄色点数量、毳毛数量和仅含一根毛发的毳毛数量以及滤泡周围色素沉着的毛囊开口百分比显著增加(p<0.05)。AGA 患者的细发(<0.03mm)比例明显高于健康对照组(p<0.05)。
我们的研究表明,AGA 患者的毛发镜检查具有重要意义。定期的临床和毛发镜随访对于监测疾病活动和治疗耐受性非常重要。