牛乳骨桥蛋白对……初始黏附的抑制作用。你提供的原文似乎不完整，最后的“of”后面缺少具体内容。

Inhibitory effect of bovine milk osteopontin on the initial attachment of .

作者信息

Ishizuka Hisako, Ishihara Kazuna, Yonezawa Hideo, Ishihara Kazuyuki, Muramatsu Takashi

机构信息

Department of Operative Dentistry, Cariology and Pulp Biology, Tokyo Dental College, Tokyo 101-0061, Japan.

Department of Microbiology, Tokyo Dental College, Tokyo 101-0061, Japan.

出版信息

JDS Commun. 2024 Apr 20;5(6):535-538. doi: 10.3168/jdsc.2024-0558. eCollection 2024 Nov.

DOI:10.3168/jdsc.2024-0558

PMID:39650014

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11624352/

Abstract

We investigated the effect of bovine milk osteopontin (OPN) on the initial adhesion of to hydroxyapatite. Hydroxyapatite pellets were immersed in a 5.4 µ OPN solution at 37°C for 30 min. As a control, Milli-Q water was used. were incubated at 37°C for 2 h on the pellets. Crystal violet staining and the quantitation of DNA were evaluated. Violet staining was observed on the hydroxyapatite pellets in the control group, but faint staining was seen in the OPN group. The amount of DNA attached to the hydroxyapatite pellet was significantly lower in the OPN group. These results suggest that initial adhesion of to the hydroxyapatite is inhibited with OPN.

摘要

我们研究了牛乳骨桥蛋白（OPN）对（此处原文缺失具体细胞或物质名称）与羟基磷灰石初始黏附的影响。将羟基磷灰石颗粒在37°C下浸入5.4 µ的OPN溶液中30分钟。作为对照，使用超纯水。（此处原文缺失具体细胞或物质名称）在颗粒上于37°C孵育2小时。评估结晶紫染色和DNA定量。对照组的羟基磷灰石颗粒上观察到紫色染色，但OPN组染色较淡。OPN组中附着在羟基磷灰石颗粒上的DNA量显著较低。这些结果表明，OPN可抑制（此处原文缺失具体细胞或物质名称）与羟基磷灰石的初始黏附。