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37个大型奶牛场干奶牛治疗部分直接成本的差异

Variation in partial direct costs of dry cow therapy on 37 large dairy herds.

作者信息

Leite de Campos J, Kates A, Steinberger A, Sethi A, Suen G, Shutske John, Safdar N, Goldberg Tony, Ruegg P L

机构信息

Department of Animal Science, Michigan State University, East Lansing, MI 48824.

Department of Medicine, University of Wisconsin-Madison, Madison, WI 53705.

出版信息

JDS Commun. 2024 May 10;5(6):639-643. doi: 10.3168/jdsc.2024-0568. eCollection 2024 Nov.

DOI:10.3168/jdsc.2024-0568
PMID:39650015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11624336/
Abstract

The objective of this observational study was to estimate partial direct costs of dry cow antibiotic therapy (DCT) protocols used on 37 large dairy herds in Wisconsin and to estimate the potential monetary savings and reduction in antimicrobial usage (AMU) if selective DCT was used. Partial direct costs of DCT were calculated using costs of intramammary (IMM) antimicrobials and teat sealants. Data were retrospectively collected on 37 large dairy farms for a period of 1 yr and included the total number of cows dried off, types of IMM antimicrobial used, and product prices (obtained from farm invoices). A single farm visit was performed to verify data. Clinical mastitis (CM) and SCC history across lactation were used as the criteria to identify cows eligible to receive only teat sealants (no antibiotic DCT) based on adoption of a hypothetical selective DCT program. Descriptive statistics were performed using PROC MEANS to summarize continuous herd and cow characteristics. Differences in costs among IMM antibiotic products and eligibility to not receive antibiotics at dry-off by parity were analyzed using ANOVA. Differences in milk yield at the last test-day and DIM at dry-off based on eligibility for selective DCT were analyzed using PROC MIXED. A total of 35,691 cows were dried off across all herds (n = 37) and most of the herds used IMM antibiotic DCT at dry-off in most of the cows. Teat sealant was used as part of the dry-off protocol in all but 3 herds. Of the enrolled farms, 30 used blanket antibiotic DCT in all quarters of all cows and 7 herds used selective DCT with no administration of antibiotics given to 0.8% to 58% of the dry cows within the herd. Across all farms, the average cost of products given per dried cow was $19.57 ± 0.64 (mean ± SE) and ranged from $8.72 to $24.04. As expected, the cost per dried cow was greater ($23.45 ± $0.38) in herds that used higher cost IMM antibiotics as compared with herds that used lower cost IMM antibiotics ($16.64 ± $0.40). When using an algorithm based on udder health records to hypothetically select cows that would be eligible to receive teat sealants only (no antibiotic DCT), eligibility ranged from 27.3% to 93.3% within-herds and varied by parity, milk yield at last test-day, and DIM at dry-off. If a selective DCT program based on udder health records was used, an overall reduction of $5.37 (27% of total costs) per dry cow would be expected. Likewise, adoption of selective DCT based on udder health records would reduce AMU at dry-off by approximately 51%. However, neither of these estimates included potential adverse health complications (such as increased CM) that can occur if selective DCT programs are not effectively performed. Variations in partial direct costs at dry-off were observed among herds based on treatment protocols. In herds that have good udder health management and contagious mastitis pathogens controlled, adoption of selective DCT based on SCC and history of CM can reduce AMU and partial direct costs of dry cow management.

摘要

这项观察性研究的目的是估算威斯康星州37个大型奶牛场使用的干奶牛抗生素治疗(DCT)方案的部分直接成本,并估算如果采用选择性DCT可能节省的资金以及抗菌药物使用量(AMU)的减少情况。DCT的部分直接成本使用乳房内(IMM)抗菌药物和乳头封闭剂的成本来计算。回顾性收集了37个大型奶牛场1年期间的数据,包括干奶的奶牛总数、使用的IMM抗菌药物类型以及产品价格(从农场发票获取)。进行了一次农场走访以核实数据。根据假设的选择性DCT方案的采用情况,将整个泌乳期的临床乳腺炎(CM)和体细胞计数(SCC)历史记录用作确定仅符合接受乳头封闭剂(不进行抗生素DCT)条件的奶牛的标准。使用PROC MEANS进行描述性统计以总结牛群和奶牛的连续特征。使用方差分析(ANOVA)分析IMM抗生素产品之间的成本差异以及按胎次划分的干奶期不接受抗生素的资格差异。使用PROC MIXED分析基于选择性DCT资格的最后测试日牛奶产量和干奶期天数(DIM)的差异。所有牛群(n = 37)中共有35,691头奶牛干奶,大多数牛群在大多数奶牛的干奶期使用IMM抗生素DCT。除3个牛群外,所有牛群都将乳头封闭剂用作干奶方案的一部分。在登记的农场中,30个农场在所有奶牛的所有乳区都使用全面抗生素DCT,7个牛群使用选择性DCT,牛群中0.8%至58%的干奶牛不使用抗生素。在所有农场中,每头干奶牛使用产品的平均成本为19.57美元±0.64美元(均值±标准误),范围为8.72美元至24.04美元。正如预期的那样,与使用低成本IMM抗生素的牛群(16.64美元±0.40美元)相比,使用高成本IMM抗生素的牛群中每头干奶牛的成本更高(23.

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