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2型Wellens综合征的紧急经皮冠状动脉介入治疗:一例老年患者非典型表现的病例报告

Urgent percutaneous coronary intervention in type 2 Wellens' syndrome: A case report of an atypical presentation in an elderly patient.

作者信息

Diallo Thierno Hamidou, Djafarou Boubacar Raynatou, Azday Illy Sawssen, Fellat Rokya, Fellat Nadia

机构信息

Cardiology A Department, Ibn Sina University Hospital Center, Rabat, Morocco.

出版信息

SAGE Open Med Case Rep. 2024 Dec 6;12:2050313X241271771. doi: 10.1177/2050313X241271771. eCollection 2024.

DOI:10.1177/2050313X241271771
PMID:39650170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11622294/
Abstract

Traditionally reflecting critical stenosis of the proximal left anterior descending (LAD) artery, Wellens' syndrome (WS) is an electrocardiogram (ECG) pattern of biphasic or deeply inverted T waves in leads V2 and V3. This critical stenosis can progress to an extensive anterior myocardial infarction (MI) if early and appropriate management is not received promptly. The diagnosis of severe stenosis of the LAD coronary artery can be made by using electrocardiographic changes in Wellens' syndrome. Due to the significant area that the LAD vascularizes, patients who exhibit symptoms and test results suggestive of this syndrome should be referred right away for an angiographic exploration in order to confirm the diagnosis and guide treatment. We report a case of a 71-year-old male admitted to our department for acute chest pain. His ECG showed Wellens' syndrome type 2 during both chest pain and pain free with slightly elevated troponin. His TIMI score was 3 and the GRACE score was 136. Critical stenosis of the LAD coronary artery was found in the coronary angiography, which required a drug-eluting stent. The patient was discharged asymptomatic from medical therapy. The diagnosis was established on the basis of the patient's interview, ECG analysis, and coronary angiography.

摘要

韦伦斯综合征(WS)传统上反映左前降支(LAD)近端的严重狭窄,是V2和V3导联出现双向或深倒置T波的心电图(ECG)模式。如果不及早进行适当治疗,这种严重狭窄可能会进展为大面积前壁心肌梗死(MI)。LAD冠状动脉严重狭窄的诊断可通过韦伦斯综合征的心电图变化来做出。由于LAD供血的区域很大,出现提示该综合征症状和检查结果的患者应立即转诊进行血管造影检查,以确诊并指导治疗。我们报告一例71岁男性因急性胸痛入住我科。他的心电图在胸痛发作时和胸痛缓解时均显示为2型韦伦斯综合征,肌钙蛋白略有升高。他的TIMI评分为3分,GRACE评分为136分。冠状动脉造影发现LAD冠状动脉严重狭窄,需要植入药物洗脱支架。患者经药物治疗后无症状出院。诊断是根据患者的病史、心电图分析和冠状动脉造影确定的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a97/11622294/cae6d5c16651/10.1177_2050313X241271771-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a97/11622294/e245bd035c17/10.1177_2050313X241271771-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a97/11622294/cae6d5c16651/10.1177_2050313X241271771-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a97/11622294/e245bd035c17/10.1177_2050313X241271771-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a97/11622294/cae6d5c16651/10.1177_2050313X241271771-fig2.jpg

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本文引用的文献

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Wellens Syndrome: prevalence, risk factors and coronary angiographic variation. A cross-sectional study.Wellens 综合征:患病率、危险因素和冠状动脉造影变异。一项横断面研究。
BMC Cardiovasc Disord. 2024 Feb 1;24(1):84. doi: 10.1186/s12872-024-03752-y.
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Characteristics of Wellens' Syndrome in the Current PCI Era: A Single-Center Retrospective Study.当前PCI时代Wellens综合征的特征:一项单中心回顾性研究
Emerg Med Int. 2023 Mar 24;2023:8865553. doi: 10.1155/2023/8865553. eCollection 2023.
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Wellens syndrome: An important consideration in patients with chest pain.Wellens综合征:胸痛患者的一个重要考量因素。
JAAPA. 2023 Feb 1;36(2):25-29. doi: 10.1097/01.JAA.0000911188.18646.31.
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Wellens' Syndrome: A Sign of Impending Myocardial Infarction.Wellens综合征:即将发生心肌梗死的征兆。
Cureus. 2022 Jun 19;14(6):e26084. doi: 10.7759/cureus.26084. eCollection 2022 Jun.
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Wellens' syndrome: incidence, characteristics, and long-term clinical outcomes.Wellens综合征:发病率、特征及长期临床结局
BMC Cardiovasc Disord. 2022 Apr 16;22(1):176. doi: 10.1186/s12872-022-02560-6.
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Pseudo-Wellens syndrome from sepsis-induced cardiomyopathy: a case report and review of the literature.脓毒症诱发的心肌病所致假性Wellens综合征:一例病例报告及文献复习
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Prevalence and Clinical Implication of Wellens' Sign in Patients With Non-ST-Segment Elevation Myocardial Infarction.非ST段抬高型心肌梗死患者中Wellens征的患病率及临床意义
Cardiol Res. 2019 Jun;10(3):135-141. doi: 10.14740/cr856. Epub 2019 Jun 7.
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Wellens' syndrome: a close call.韦伦综合征:一次险些误诊的情况。
BMJ Case Rep. 2018 Jun 21;2018:bcr-2018-225376. doi: 10.1136/bcr-2018-225376.
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CARE guidelines for case reports: explanation and elaboration document.病例报告的CARE指南:解释与阐述文件。
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