Erasmus Shannah, Lyu Zhengyi, Zhou Jie, Fang Jianqiao, Liang Yi
International Education College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People's Republic of China.
The Third Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People's Republic of China.
J Pain Res. 2024 Dec 4;17:4089-4100. doi: 10.2147/JPR.S498373. eCollection 2024.
Postoperative hyperalgesic priming, exacerbated by preoperative anxiety, complicates pain management and recovery. Electroacupuncture (EA), a technique that combines traditional acupuncture with electrical stimulation applied through needles to enhance therapeutic effect, offers a potential solution by targeting multiple neurobiological pathways.
This review investigates how EA addresses preoperative anxiety-induced postoperative hyperalgesic priming ie pain chronification, focusing on its mechanisms in three areas: preoperative anxiety, postoperative hyperalgesic priming, and the interaction between EA and these processes.
A literature search across PubMed, ScienceDirect, and Google Scholar identified relevant studies on EA's effects on neurobiological pathways related to anxiety and pain. The review synthesized findings to understand EA's role in these contexts.
EA alleviates preoperative anxiety by influencing the body's neurochemical and neurophysiological responses. It reduces inflammation, regulates stress hormones, and improves autonomic function. For postoperative pain chronification, EA modulates pain pathways, reduces inflammation, and affects receptor signaling, gene expression, and neurotransmitter systems.
EA offers a promising approach to managing preoperative anxiety and postoperative pain. By addressing both the physiological and neurochemical pathways that contribute to pain and anxiety, EA has the potential to significantly improve clinical outcomes for patients undergoing surgery. Further research is needed to fully understand its mechanisms and optimize its application in clinical settings.
术后痛觉过敏预激,因术前焦虑而加剧,使疼痛管理和恢复变得复杂。电针疗法(EA)是一种将传统针刺与通过针施加电刺激相结合以增强治疗效果的技术,通过针对多种神经生物学途径提供了一种潜在的解决方案。
本综述研究电针疗法如何解决术前焦虑引起的术后痛觉过敏预激即疼痛慢性化问题,重点关注其在三个方面的机制:术前焦虑、术后痛觉过敏预激以及电针疗法与这些过程之间的相互作用。
在PubMed、ScienceDirect和谷歌学术上进行文献检索,以确定有关电针疗法对与焦虑和疼痛相关的神经生物学途径影响的相关研究。该综述综合研究结果以了解电针疗法在这些背景下的作用。
电针疗法通过影响身体的神经化学和神经生理反应来减轻术前焦虑。它减轻炎症、调节应激激素并改善自主神经功能。对于术后疼痛慢性化,电针疗法调节疼痛途径、减轻炎症并影响受体信号传导、基因表达和神经递质系统。
电针疗法为管理术前焦虑和术后疼痛提供了一种有前景的方法。通过解决导致疼痛和焦虑的生理和神经化学途径,电针疗法有可能显著改善手术患者的临床结局。需要进一步研究以充分了解其机制并优化其在临床环境中的应用。