Zhao Xiuzhen, Liu Linxi, Diao Yingxiu, Ma Chunling
The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, China.
Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
Front Neurol. 2024 Nov 22;15:1480681. doi: 10.3389/fneur.2024.1480681. eCollection 2024.
Electroacupuncture (EA) has been employed to address the symptoms of constipation in individuals who have experienced a stroke. However, supporting evidence for its efficacy is lacking. This meta-analysis aims to investigate whether EA was effective in treating poststroke constipation.
We conducted a comprehensive search of eight databases, including four English-language databases (PubMed, Embase, Web of Science, and the Cochrane Library) and four Chinese-language databases (Chinese Biomedical Literature Database, China National Knowledge Infrastructure, VIP, and Wanfang), for randomized controlled trials (RCTs) published from inception through January 31, 2023. To assess treatment effectiveness, we calculated the risk ratio (RR) or mean difference (MD) with 95% confidence interval (CI).
A total of 9 RCTs involving 601 participants were included. No heterogeneity was found across the included RCTs. The results of this meta-analysis indicated significant improvements in the total effective rate (RR = 1.39, 95% CI 1.27, 1.52), cure rates (RR 1.87, 95% CI 1.38, 2.54), constipation scoring system (MD = -2.51, 95% CI -3.05, -1.97), and quality of life (MD = -10.69, 95% CI -14.2, -7.17) in the EA group compared with the control group.
Current evidence indicates that EA may be recommended for patients experiencing poststroke constipation. The lack of thorough investigations has undermined the quality of the major findings.
电针已被用于治疗中风患者的便秘症状。然而，其疗效缺乏支持证据。本荟萃分析旨在研究电针治疗中风后便秘是否有效。
我们全面检索了八个数据库，包括四个英文数据库（PubMed、Embase、Web of Science和Cochrane图书馆）和四个中文数据库（中国生物医学文献数据库、中国知网、维普和万方），以查找从数据库建库至2023年1月31日发表的随机对照试验（RCT）。为评估治疗效果，我们计算了风险比（RR）或平均差（MD）以及95%置信区间（CI）。
共纳入9项RCT，涉及601名参与者。纳入的RCT之间未发现异质性。本荟萃分析结果表明，与对照组相比，电针组的总有效率（RR = 1.39，95% CI 1.27，1.52）、治愈率（RR 1.87，95% CI 1.38，2.54）、便秘评分系统（MD = -2.51，95% CI -3.05，-1.97）和生活质量（MD = -10.69，95% CI -14.2，-7.17）均有显著改善。
目前的证据表明，对于中风后便秘患者，可推荐使用电针。但缺乏深入研究影响了主要研究结果的质量。
