Fradkin Isaac, Adams Rick A, Siegelman Noam, Moran Rani, Dolan Raymond J
Max Planck University College London Centre for Computational Psychiatry and Ageing Research, London, UK.
Department of Psychology, Hebrew University of Jerusalem, Jerusalem, Israel.
Nat Ment Health. 2024;2(12):1486-1497. doi: 10.1038/s44220-024-00351-w. Epub 2024 Nov 25.
Comprehensible communication is critical for social functioning and well-being. In psychopathology, incoherent discourse is assumed to reflect disorganized thinking, which is classically linked to psychotic disorders. However, people do not express everything that comes to mind, rendering inferences from discourse to the underlying structure of thought challenging. Indeed, a range of psychopathologies are linked to self-reported disorganized thinking in the absence of language output incoherence. Here we combine natural language processing and computational modeling of free association to detail the relationship between disorganized thinking and language (in)coherence in a large sample of participants varying across different dimensions of psychopathology. Our approach allowed us to differentiate between disorganized thinking, disinhibited thought expression and deliberate creativity. We find evidence for both under-regulated and over-regulated disorganized thinking, which relate to two specific dimensions of psychopathology: self-reported eccentricity and suspiciousness. Broadly, these results underscore the theoretical progress afforded by analyzing latent dimensions underlying behavior and psychopathology.
可理解的沟通对于社会功能和幸福感至关重要。在精神病理学中,语无伦次的话语被认为反映了思维紊乱,这在传统上与精神障碍有关。然而,人们不会表达出脑海中出现的所有想法,这使得从话语推断潜在思维结构具有挑战性。事实上,一系列精神病理学与自我报告的思维紊乱有关,而此时语言输出并无连贯性。在这里,我们将自然语言处理和自由联想的计算模型相结合,以详细阐述在一大群精神病理学不同维度各异的参与者中,思维紊乱与语言(非)连贯性之间的关系。我们的方法使我们能够区分思维紊乱、思维表达不受抑制和刻意创造力。我们发现了思维紊乱调节不足和调节过度的证据,它们与精神病理学的两个特定维度相关:自我报告的古怪和多疑。总体而言,这些结果强调了通过分析行为和精神病理学背后的潜在维度所取得的理论进展。