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自闭症前期:推进自闭症的早期识别与干预

Pre-autism: Advancing early identification and intervention in autism.

作者信息

Al-Beltagi Mohammed

机构信息

Department of Pediatric, Faculty of Medicine, Tanta University, Tanta ‎31511‎, Egypt.

Department of Pediatric, University Medical Center, King Abdulla Medical City, Arabian Gulf University, Manama 26671, Bahrain.

出版信息

World J Clin Cases. 2024 Dec 6;12(34):6748-6753. doi: 10.12998/wjcc.v12.i34.6748.

Abstract

Autism spectrum disorder (ASD) is often diagnosed long after symptoms have become noticeable. This delay can make it difficult to provide early intervention, which can impact long-term outcomes. The concept of "pre-autism" highlights the phase before a formal diagnosis of ASD, providing an opportunity for earlier identification and intervention, which could be a turning point in ASD management. In a previous article, we explored different ways of diagnosing pre-autism, including historical records, physical markers, laboratory tests, and radiological evidence. This manuscript builds on that foundation by emphasizing the importance of early diagnosis and intervention in ASD. Recent research advancements have clarified that ASD presentations can be complex, and individualized support strategies are necessary. The significance of pre-autism lies in its potential to alter the trajectory of ASD through early detection and intervention despite challenges such as limited awareness and variability in symptom presentation. Biomarkers and diagnostic tools have shown promise as avenues for early detection, but it is essential to exercise caution and not rely too heavily on yet-to-be-established markers. Addressing these challenges requires a collaborative effort to increase awareness, improve access to diagnostic tools, and foster inclusive environments. Ultimately, this manuscript calls for ongoing research, advocacy, and resource allocation to enhance early detection and intervention efforts, ensuring optimal outcomes for individuals on the autism spectrum.

摘要

自闭症谱系障碍(ASD)通常在症状变得明显很久之后才被诊断出来。这种延迟会使早期干预变得困难,而早期干预会影响长期预后。“自闭症前期”的概念突出了在正式诊断ASD之前的阶段,为更早的识别和干预提供了机会,这可能是ASD管理中的一个转折点。在之前的一篇文章中,我们探讨了诊断自闭症前期的不同方法,包括历史记录、身体指标、实验室检查和影像学证据。本文在此基础上,强调了ASD早期诊断和干预的重要性。最近的研究进展表明,ASD的表现可能很复杂,个性化的支持策略是必要的。自闭症前期的重要性在于,尽管存在认识有限和症状表现各异等挑战,但它有可能通过早期检测和干预改变ASD的发展轨迹。生物标志物和诊断工具已显示出作为早期检测途径的前景,但必须谨慎行事,不要过于依赖尚未确定的标志物。应对这些挑战需要共同努力,以提高认识、改善诊断工具的可及性并营造包容的环境。最终,本文呼吁持续开展研究、宣传和资源分配,以加强早期检测和干预工作,确保自闭症谱系障碍患者获得最佳预后。

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