Alsaegh Ahmed, Khamdan Zainab, Ahmed Jalila, Marhoon Maryam, Ahmed Amina, Alderazi Adoub, Husain Hoor
Gastroenterology and Hepatology, Salmaniya Medical Complex, Manama, BHR.
Internal Medicine, Salmaniya Medical Complex, Manama, BHR.
Cureus. 2024 Nov 8;16(11):e73270. doi: 10.7759/cureus.73270. eCollection 2024 Nov.
Autoimmune pancreatitis (AIP) is a rare form of pancreatitis. This case report focuses on type 1 autoimmune pancreatitis (AIP-1), an immunoglobulin G4 (IgG4)-related disease. It is characterized by dense infiltration of lymphocytes and plasma cells, primarily in a periductal distribution. We report a case of a 48-year-old man diagnosed with AIP-1 who subsequently developed eccrine chromhidrosis and bilioptysis during the peak of bilirubin level. This case highlights the diagnostic process followed to identify this challenging condition and demonstrates the patient's response to the mainstay treatment. Moreover, it discusses the rare symptoms that can manifest with marked hyperbilirubinemia.
自身免疫性胰腺炎（AIP）是一种罕见的胰腺炎形式。本病例报告聚焦于1型自身免疫性胰腺炎（AIP-1），一种与免疫球蛋白G4（IgG4）相关的疾病。其特征是淋巴细胞和浆细胞密集浸润，主要呈导管周围分布。我们报告一例48岁男性被诊断为AIP-1，在胆红素水平达到峰值时随后出现了小汗腺色汗症和胆汁咳出。本病例突出了识别这种具有挑战性疾病所遵循的诊断过程，并展示了患者对主要治疗方法的反应。此外，还讨论了显著高胆红素血症时可能出现的罕见症状。
