Alandejani Mohammad, Radi Suhaib, Tashkandi Ammar, Alzahrani Jehad
Department of Internal Medicine, Division of Endocrinology, Ministry of National Guard-Health Affairs, Jeddah, SAU.
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Cureus. 2024 Nov 7;16(11):e73202. doi: 10.7759/cureus.73202. eCollection 2024 Nov.
Concomitant medullary thyroid carcinoma and papillary thyroid carcinoma in the thyroid gland are rare; however, the incidence is increasing. Here, we present the case of a 77-year-old male who was incidentally found to have thyroid nodules after a road traffic accident. Fine-needle aspiration revealed two inconclusive Bethesda classifications: follicular neoplasm and unsatisfactory. The diagnosis of concomitant medullary thyroid carcinoma and papillary thyroid carcinoma was later confirmed by histopathology results after total thyroidectomy. The selected treatment was a total thyroidectomy in addition to radioactive iodine later on due to complications of invasion of the trachea. This case focuses on the possibility of having multiple types of carcinoma in a single thyroid gland.
甲状腺内同时存在髓样甲状腺癌和乳头状甲状腺癌的情况较为罕见;然而,其发病率正在上升。在此,我们报告一例77岁男性病例,该患者在道路交通事故后偶然发现甲状腺结节。细针穿刺显示两种不确定的贝塞斯达分类:滤泡性肿瘤和不满意分类。全甲状腺切除术后的组织病理学结果后来证实了同时存在髓样甲状腺癌和乳头状甲状腺癌的诊断。由于气管受侵的并发症,后续选择的治疗方法是全甲状腺切除术加放射性碘治疗。本病例重点关注单个甲状腺内存在多种类型癌症的可能性。