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下颌骨骨内黏液表皮样癌:两例报告及文献复习

Intraosseous Mucoepidermoid Carcinoma in the Mandible: A Report of Two Cases and Literature Review.

作者信息

Majeed Abid, Sethi Alok K, Bhat Damodar, Jena Ashok K, Mishra Pritinanda

机构信息

Department of Dentistry, All India Institute of Medical Sciences, Bhubaneswar, Bhubaneswar, IND.

Department of Pathology, All India Institute of Medical Sciences, Bhubaneswar, Bhubaneswar, IND.

出版信息

Cureus. 2024 Nov 6;16(11):e73143. doi: 10.7759/cureus.73143. eCollection 2024 Nov.

Abstract

Mucoepidermoid carcinoma (MEC) is the most common malignant tumor of salivary glands.It usually occurs in major salivary glands. The occurrence of intraosseous MEC (IMEC) is rare and is usually seen in the mandibular premolar and molar regions.These tumors present mixed radiolucent and radiopaque images on radiographs, which makes the diagnosis difficult. Thus, histopathological evaluation is the definitive and accurate method for its diagnosis. The treatment depends on the histopathological grading of the tumors. Low-grade tumors are usually treated with radical resection surgeries, and high-grade ones need definitive radiotherapy in addition to radical resection surgeries and neck dissection. Intraosseous involvement of MEC in the mandible is rare. This manuscript highlights the clinical presentation and management of two cases of IMEC of the mandible.

摘要

黏液表皮样癌(MEC)是唾液腺最常见的恶性肿瘤。它通常发生于大唾液腺。骨内黏液表皮样癌(IMEC)的发生较为罕见,通常见于下颌前磨牙和磨牙区。这些肿瘤在X线片上呈现出透射线和阻射线混合的影像,这使得诊断困难。因此,组织病理学评估是其诊断的决定性且准确的方法。治疗取决于肿瘤的组织病理学分级。低级别肿瘤通常采用根治性切除手术治疗,而高级别肿瘤除了根治性切除手术和颈部清扫外,还需要确定性放疗。MEC在下颌骨的骨内累及情况罕见。本文着重介绍了两例下颌骨IMEC的临床表现及治疗。

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