Ina Emily A, Ziton Shirley, Dourvetakis Kirk, Corallo Joseph P
Osteopathic Medical School, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
General Surgery, Broward Health Medical Center, Fort Lauderdale, USA.
Cureus. 2024 Nov 6;16(11):e73141. doi: 10.7759/cureus.73141. eCollection 2024 Nov.
Fulminant colitis is a severe and potentially life-threatening form of associated bacterial disease leading to inflammation and damage to the colon. Complications such as toxic megacolon, sepsis, and multi-organ failure commonly occur in individuals with compromised immune systems and recent antibiotic use. Management of colitis involves optimization of fluid and electrolyte balance, and elimination of bacteria commonly by administering vancomycin or fidaxomicin. In cases where pharmacological management has been ineffective, fecal microbiota transplantation and surgical intervention demonstrated success. Historically, surgical intervention has involved a total abdominal colectomy with end ileostomy; however, other surgical options have shown increasing benefits with preservation of the colon. This case report aims to provide an example of an alternative management strategy for fulminant infections, via the use of a loop ileostomy and colonic lavage. The combination of loop ileostomy and colonic lavage promotes bowel rest, removes toxins, and promotes healing while decreasing inflammation. As with all management modalities, it is essential to recognize the associated complications. The potential benefits should be carefully weighed against the risks on a case-by-case basis with the help of a multidisciplinary team as illustrated through this case report. Overall, early recognition and treatment of fulminant colitis using loop ileostomy and colonic lavage prevents further disease progression and improves patient outcomes.
暴发性结肠炎是一种严重且可能危及生命的相关细菌性疾病,会导致结肠炎症和损伤。中毒性巨结肠、败血症和多器官功能衰竭等并发症常见于免疫系统受损和近期使用过抗生素的个体。结肠炎的治疗包括优化液体和电解质平衡,通常通过使用万古霉素或非达霉素来清除细菌。在药物治疗无效的情况下,粪便微生物群移植和手术干预已显示出成效。从历史上看,手术干预包括全腹结肠切除术并进行回肠造口术;然而,其他手术选择在保留结肠方面显示出越来越多的益处。本病例报告旨在提供一个通过使用袢式回肠造口术和结肠灌洗来治疗暴发性感染的替代管理策略的示例。袢式回肠造口术和结肠灌洗相结合可促进肠道休息、清除毒素、促进愈合并减轻炎症。与所有管理方式一样,认识到相关并发症至关重要。正如本病例报告所示,在多学科团队的帮助下,应根据具体情况仔细权衡潜在益处与风险。总体而言,使用袢式回肠造口术和结肠灌洗对暴发性结肠炎进行早期识别和治疗可防止疾病进一步进展并改善患者预后。